Explore the latest in gastrointestinal cancer, including advances in management of esophageal, gastric, colorectal, and pancreatic malignancy.
This randomized clinical trial compares the effects of fruquintinib, a vascular endothelial growth factor receptor (VEGFR) inhibitor, vs placebo on overall survival among patients with metastatic colorectal cancer whose disease progressed on treatment or who could not tolerate standard treatment because of toxic effects.
This case-control study uses Mayo Clinic registry data to assess associations between inherited germline mutations in 21 cancer predisposition genes and risk of pancreatic cancer.
This study compares preoperative chemoradiation followed by postoperative adjuvant chemotherapy vs total neoadjuvant therapy for treatment of locally advanced rectal cancer.
This secondary analysis of a randomized clinical trial investigates the prognostic role of the total mesorectal excision plane quality in patients with rectal cancer who were treated within the CAO/ARO/AIO-04 phase 3 randomized clinical trial.
This study evaluates the use of a comprehensive screening protocol for prostate, breast, colorectal, and pancreatic cancer and skin malignant abnormalities in male BRCA carriers.
This genetic sequencing study explores whether up-front tumor sequencing can replace the prevailing paradigm for universal tumor screening for Lynch syndrome, which includes a sequence of several screening tests.
This cohort study of patients with stage III colon cancer enrolled in the CALGB 89803/Alliance trial evaluated the association of survival rates with adherence to the American Cancer Society Nutrition and Physical Activity Guidelines for Cancer Survivors.
This nonrandomized, noncontrolled clinical trial evaluates the 6-month progression-free survival, tumor objective response, and overall survival rates in patients with gastrointestinal stromal tumors treated with dasatinib.
This randomized controlled trial compares the effects of high- vs low-frequency computed tomographic and carcinoembryonic antigen surveillance on 5-year overall mortality and colorectal cancer–specific mortality rates among patients with stage II and II colorectal cancer after curative resection.
This cohort study uses medical record data to compare disease recurrence among patients with stages I, II, or III colorectal cancer monitored with higher- vs lower-intensity imaging and CEA surveillance testing within 3 years after treatment.
This study analyzes the association of BRAF and KRAS mutational status with overall and disease-free survival among patients undergoing hepatectomy for colorectal liver metastases.
This cohort study of participants in the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer randomized clinical trial compares long-term CRC incidence between individuals with either advanced or nonadvanced adenomas compared with those with no adenomas.
This cohort study evaluates the changes in the amount of muscular and adipose tissue before and after neoadjuvant therapy in patients with pancreatic cancer.
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