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    Heart Failure

    Explore the latest in heart failure, including recent guidelines and advances in treatment of HF with reduced and preserved ejection fraction.

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    • Assessing Heart Failure vs Lymphoma Treatment Risks and Benefits—It Takes Two to Tango
      JAMA Cardiology
      Opinion
      March 29, 2023
      Cardiology Hematology Oncology Hematologic Cancer Lymphomas
      Full Text | pdf link PDF has multimedia
    • Association of Preexisting Heart Failure With Outcomes in Older Patients With Diffuse Large B-Cell Lymphoma
      JAMA Cardiology
      Research
      March 29, 2023

      This cohort study assesses the prevalence of preexisting heart failure in older patients with diffuse large B-cell lymphoma and its association with treatment patterns and outcomes using data from the Surveillance, Epidemiology, and End Results–Medicare registry.

      Cardiology Oncology Hematologic Cancer Lymphomas Hematology
      Full Text | pdf link PDF has multimedia
    • Virtual Care Teams Improved Guideline Adoption for Heart Failure
      JAMA
      News
      March 15, 2023
      Cardiology Health Care Delivery Models Health Policy Mobile Health and Telemedicine
      Full Text | pdf link PDF free
    • Seizure Drug Increased Heart Donor Storage Time, Improved Function
      JAMA
      News
      March 14, 2023
      Cardiology Cardiothoracic Surgery Surgery Transplantation
      Full Text | pdf link PDF free
    • Rate-Adaptive Atrial Pacing for Heart Failure With Preserved Ejection Fraction: The RAPID-HF Randomized Clinical Trial
      JAMA
      Research
      March 14, 2023

      This randomized crossover trial assessed if implanting and programming a pacemaker for rate-adaptive atrial pacing improved exercise performance in patients with heart failure with preserved ejection fraction and chronotropic incompetence at a single US tertiary referral center.

      Cardiology Heart Failure with Preserved Ejection Fraction
      Full Text | pdf link PDF
    • Heart Failure With Preserved Ejection Fraction: A Review
      JAMA
      Review
      March 14, 2023

      This review discusses current evidence regarding the epidemiology, pathophysiology, clinical presentation, diagnosis, and management of heart failure with preserved ejection fraction.

      Cardiology Heart Failure with Preserved Ejection Fraction
      Full Text | pdf link PDF | CME & MOC is active quiz has multimedia
    • Rate-Adaptive Pacing for Heart Failure With Preserved Ejection Fraction
      JAMA
      Opinion
      March 14, 2023
      Cardiology Heart Failure with Preserved Ejection Fraction
      Full Text | pdf link PDF
    • Effect of Sacubitril/Valsartan vs Valsartan on Left Atrial Volume in Patients With Pre–Heart Failure With Preserved Ejection Fraction: The PARABLE Randomized Clinical Trial
      JAMA Cardiology
      Research
      March 8, 2023

      This randomized clinical trial evaluates the efficacy of sacubitril/valsartan vs valsartan in the treatment of left ventricular diastolic function in patients with pre–heart failure with preserved ejection fraction.

      Heart Failure with Preserved Ejection Fraction Cardiology
      Full Text | pdf link PDF open access
    • Cost-effectiveness of Sodium-Glucose Cotransporter-2 Inhibitors for the Treatment of Heart Failure With Preserved Ejection Fraction
      JAMA Cardiology
      Research
      March 4, 2023

      This economic evaluation investigates if the addition of a sodium-glucose cotransporter-2 inhibitor to standard therapy would be cost-effective in individuals with heart failure and preserved ejection fraction.

      Pharmacoeconomics Cardiology Heart Failure with Preserved Ejection Fraction
      Full Text | pdf link PDF
    • Cost-effectiveness of Sodium-Glucose Cotransporter-2 Inhibitors for Patients With Heart Failure and Preserved Ejection Fraction—Living on the Edge
      JAMA Cardiology
      Opinion
      March 4, 2023
      Cardiology Heart Failure with Preserved Ejection Fraction Pharmacoeconomics
      Full Text | pdf link PDF
    • Association of Long-term Change in N-Terminal Pro–B-Type Natriuretic Peptide With Incident Heart Failure and Death
      JAMA Cardiology
      Research
      March 1, 2023

      This cohort study assesses the association between change in N-terminal pro–B-type natriuretic peptide with risk for incident heart failure and death.

      Cardiology
      Full Text | pdf link PDF
    • Association of Rurality With Risk of Heart Failure
      JAMA Cardiology
      Research
      March 1, 2023

      This cohort study analyzes data for participants from the Southern Community Cohort Study to determine whether rurality is associated with increased risk of heart failure and whether rurality-associated risk varies by race and sex.

      Cardiology Health Disparities
      Full Text | pdf link PDF
    • Estimation of Out-of-Pocket Costs for Guideline-Directed Medical Therapy for Heart Failure Under Medicare Part D and the Inflation Reduction Act
      JAMA Cardiology
      Research
      March 1, 2023

      This cross-sectional study estimates out-of-pocket costs of heart failure with reduced ejection fraction medication regimens in Medicare Part D under current law and the Inflation Reduction Act.

      Health Care Economics, Insurance, Payment Health Policy Cardiology Pharmacoeconomics
      Full Text | pdf link PDF
    • Effect of Personalized Accelerated Pacing on Quality of Life, Physical Activity, and Atrial Fibrillation in Patients With Preclinical and Overt Heart Failure With Preserved Ejection Fraction: The myPACE Randomized Clinical Trial
      JAMA Cardiology
      Research
      March 1, 2023

      This randomized clinical trial assesses the effects of a moderately accelerated personalized backup heart rate compared with 60 bpm in patients with heart failure with preserved ejection fraction (HFpEF) who have preexisting pacemaker systems that limit pacemaker-mediated dyssynchrony.

      Medical Devices and Equipment Heart Failure with Preserved Ejection Fraction Cardiology Rhythm Disorders
      Full Text | pdf link PDF
    • Association of Days Alive and Out of the Hospital After Ventricular Assist Device Implantation With Adverse Events and Quality of Life
      JAMA Surgery
      Research
      February 22, 2023

      This study attempts to incidence of percent of days alive out of hospital before and after left ventricular assist device implantation and explores its association with established quality metrics.

      Medical Devices and Equipment Cardiology Cardiothoracic Surgery Surgery
      Full Text | pdf link PDF
    • Association of Dapagliflozin Use With Clinical Outcomes and the Introduction of Uric Acid–Lowering Therapy and Colchicine in Patients With Heart Failure With and Without Gout: A Patient-Level Pooled Meta-analysis of DAPA-HF and DELIVER
      JAMA Cardiology
      Research
      February 22, 2023

      This post hoc analysis of 2 randomized clinical trials analyzes data for patients with heart failure and with and without gout to gauge the effects of dapagliflozin on the risk of clinical outcomes and the new use of uric acid–lowering agents and colchicine.

      Clinical Pharmacy and Pharmacology Rheumatology Cardiology Diabetes Diabetes and Endocrinology
      Full Text | pdf link PDF open access
    • A Cautiously Optimistic Metric for Patients Undergoing Durable Left Ventricular Assist Device Implantation
      JAMA Surgery
      Opinion
      February 22, 2023
      Cardiology Surgery Medical Devices and Equipment
      Full Text | pdf link PDF
    • Quality of Care and Outcomes Among Patients Hospitalized for Heart Failure in Rural vs Urban US Hospitals: The Get With The Guidelines–Heart Failure Registry
      JAMA Cardiology
      Research
      February 20, 2023

      This cohort study assesses quality of care and clinical outcomes for US patients hospitalized for heart failure at rural vs urban hospitals in the Get With The Guidelines–Heart Failure registry.

      Cardiology Health Disparities Health Care Quality Guidelines
      Full Text | pdf link PDF
    • A Man in His 50s With an Unusual Network of Small Veins in the Left Infraclavicular Region—Paget-Schroetter Syndrome
      JAMA Cardiology
      Case Report
      February 8, 2023

      This case report describes a diagnosis of Paget-Schroetter syndrome in a man in his 50s with a network of small veins in the left infraclavicular region discovered after unsuccessful left subclavian vein puncture.

      Cardiology Venous Thromboembolism Rhythm Disorders Cardiovascular Images Emergency Medicine
      Full Text | pdf link PDF | CME & MOC is active quiz has multimedia
    • Heart Failure in Patients With Cancer Treated With Anthracyclines—Revisiting the Foundation of Cardio-Oncology
      JAMA Network Open
      Opinion
      February 3, 2023
      Cardiology Hematology Oncology Hematologic Cancer Lymphomas
      Full Text | pdf link PDF open access
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