Explore the latest in hematology from The JAMA Network, including topics in anticoagulation, bleeding and transfusion, hematologic cancers, and more.
This cohort study uses data from first-time transfusion recipients to assess the association between red blood cell transfusion from female donors with and without a history of pregnancy and mortality among red blood cell recipients.
A woman in her 30s was referred for evaluation of severe bilateral optic disc edema, retinal hemorrhages, and a gradual decrease in vision during a 3-week period. What would you do next?
A woman in her 80s presented with a 1-year history of blanchable, salmon-colored, monomorphic macules and fine telangiectasias localized to her right lower leg. What is your diagnosis?
This trainee-led quality improvement study evaluates the use of the Culture, Oversight, Systems Change, Training framework to reduce inappropriate proton pump inhibitor infusions in patients with upper gastrointestinal bleeding.
This phase 2 trial of 12 patients assesses the efficacy and safety of brentuximab vedotin for lymphomatoid papulosis.
This cohort study uses data from the Taiwan National Health Insurance database to assess the association between use of non–vitamin K oral anticoagulants with vs without concurrent medications and risk of major bleeding in patients with nonvalvular atrial fibrillation.
This population-based study characterize rates of hematuria-related complications among patients taking antithrombotic medications.
A female infant with relapsed refractory infantile acute lymphoblastic leukemia presented with several vesicles with an erythematous base on the lower back and left thigh 17 days after reinduction chemotherapy. What is your diagnosis?
This case report describes bleeding complications in 2 patients being treated with ibrutinib who underwent cutaneous surgery.
This case series assesses the visual function of 3 patients with sickle cell disease and temporal macular atrophy but with no visual symptoms.
This study uses the SEER database to explore the clinical characteristics of diffuse large B-cell lymphoma and determine factors associated with overall survival among patients with primary vitreoretinal and ocular adnexal–uveal disease.
A woman in her 60s presented with multiple painful cutaneous nodules and a history of IgGκ multiple myeloma. What is your diagnosis?
This case series describes a large single-institution experience with resuscitative endovascular balloon occlusion of the aorta for severe traumatic hemorrhage, traumatic arrest, or nontraumatic hemorrhage.
This case report describes a woman in her 40s with obscured vision in her right eye 3 years after undergoing endovascular coil embolization for a subarachnoid hemorrhage.
This Viewpoint uses FDA approval of tisagenlecleucel, the first chimeric antigen receptor T-cell (CAR-T) agent approved for human use, to discuss escalating drug prices for oncology therapies and the complex considerations of outcomes and value that should justify the pricing.
This database review evaluates the prevalence of anemia 10 years after Roux-en-Y gastric bypass and whether bariatric follow-up influences anemia rates in a population of veterans.