Explore the latest in hepatobiliary cancer, including advances in understanding the epidemiology, diagnosis, management, and prevention of the disease.
This cohort study uses UK Biobank data to estimate the risk for primary hepatic carcinoma and cancer-related death by HFE variant status among community-dwelling individuals of European ancestry in England, Scotland, and Wales.
This decision analytical model study assesses the burden of hepatocellular carcinoma surveillance in the era of new hepatitis C antiviral treatments by projecting the number and the characteristics of new hepatocellular carcinoma incident cases and candidates for routine hepatocellular carcinoma surveillance.
This randomized clinical trial assesses the efficacy of nivolumab plus ipilimumab in the treatment of patients with advanced hepatocellular carcinoma who have been previously treated with sorafenib.
This Viewpoint discusses approvals by the US Food and Drug Administration for first- and second-line chemotherapy drugs—plus the combined use of some agents—used to treat hepatocellular carcinoma.
This cohort study examined the association of adding ablative therapy to transarterial chemoembolization with overall survival and freedom from local progression among patients with hepatocellular carcinoma (HCC).
This cohort study examines the association between aspirin use and cholangiocarcinoma in an Asian cohort.
This narrative review discusses developments in pharmacotherapy for patients with advanced hepatocellular carcinoma.
This systematic review with meta-analysis compares the effectiveness of different vascular endothelial growth factor inhibitors, checkpoint inhibitors, or their combinations in patients with advanced hepatocellular carcinoma in the first-line or refractory settings.
This case report describes a woman in her 70s with type 2 diabetes, hypertension, idiopathic thrombocytopenia, and metastatic cholangiocarcinoma with an fibroblast growth factor receptor 2 translocation.
This study describes trends in the incidence of hepatocellular carcinoma within the Veterans Health Administration from 2002 to 2018 before and after widespread direct-acting anti–hepatitis C virus (HCV) treatment.
This cohort study examines very early recurrence following resection for intrahepatic cholangiocarcinoma in the preoperative and postoperative setting.
This prognostic study examines whether deep learning recurrent neural network (RNN) models that use raw longitudinal data extracted directly from electronic health records outperform conventional regression models in predicting the risk of developing hepatocellular carcinoma (HCC).
This multicenter phase 2 study evaluates the anticancer activity of nivolumab in patients with advanced refractory biliary tract cancer.
This cohort study assesses the growth pattern of gallbladder polyps and their association with gallbladder cancer.
This prognostic study evaluates the feasibility and availability of a novel hepatitis B virus DNA index to assess the prognosis of patients with hepatitis B virus–related hepatocellular carcinoma.
This randomized clinical trial compares the long-term survival outcomes after repeat hepatectomy with those after percutaneous radiofrequency ablation among patients with recurrent hepatocellular carcinoma.
This open-label, single-arm, pilot, phase 1b/2 clinical trial assesses outcomes following treatment with nab-paclitaxel plus gemcitabine plus the platinum-based cisplatin for patients with previously untreated metastatic pancreatic ductal adenocarcinoma.
This phase 2 clinical trial measures the 3-month response rate of selective internal radiotherapy combined with chemotherapy as well as toxic effects, overall and progression-free survival, and disease control rate for patients with unresectable intrahepatic cholangiocarcinoma.
This phase 2 clinical trial evaluates the use of hepatic arterial infusion of floxuridine plus systemic administration of gemcitabine and oxaliplatin in patients with unresectable intrahepatic cholangiocarcinoma.
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