Explore the latest in infectious diseases from The JAMA Network, including community-acquired and nosocomial disease, antibiotic use and stewardship, and more.
This study evaluates the use of spatial and temporal mapping to identify nosocomial disease transmission of Clostridium difficile.
This case-control study conducted during the Zika virus epidemic in Puerto Rico estimates the association between preceding Zika virus infection and subsequent Guillain-Barré syndrome.
This cohort simulation model evaluates the use of tests and treatment of latent tuberculosis infection in residents born outside the United States.
This randomized clinical trial assesses the effect of modified vaccinia Ankara–5T4, metronomic low-dose cyclophosphamide, or a combination of both treatments on antitumor immunity in patients with metastatic colorectal cancer.
This study examines assesses inappropriate antibiotic prescribing 12 months after stopping a randomized clinical trial of a behavioral intervention intended to reduce the rate of inappropriate antibiotic prescribing for acute respiratory infections.
In this Viewpoint, Anthony Fauci discusses the limits of current treatment and prevention approaches to the HIV epidemic and proposes that the addition of an HIV vaccine is necessary to slow and end it.
A 30-year-old woman with a remote history of Hemophilus influenzae type b meningitis causing quadraparesis was admitted to the hospital with Candida fungemia.
This Viewpoint summarizes what is currently known about Zika virus infection associated with hearing loss in both children and adults and points out areas where further research is needed.
In this Viewpoint, Anthony Fauci and colleagues review rapid research responses to recent infectious disease outbreaks as a way of emphasizing the strategies and collaborations necessary to prepare for a next unknown pandemic.
This cohort study compares estimates of sepsis incidence, outcomes, and trends based on clinical data from US hospital electronic health record systems vs claims-based ICD-9 data.
This study uses Centers for Disease Control and Prevention data to characterize trends in the incidence of measles among US residents from 2001 to 2015.
This cohort study assesses the validity of a pediatric version of the Sequential Organ Failure Assessment (SOFA) scoring system compared with the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) to examine the in-hospital mortality of critically ill children with confirmed or suspected infection and sepsis.
This birth surveillance study compares the risk for selected birth outcomes by maternal antiretroviral therapy regimen among pregnant women with HIV infection in Botswana.