Explore the latest in infectious diseases, including community-acquired and nosocomial disease, antibiotic use and stewardship, and more.
This randomized clinical trial compares the effects of treatment with intravenous vitamin C, hydrocortisone, and thiamine compared with intravenous hydrocortisone alone on duration of time alive and free of vasopressor use over 7 days in patients with septic shock.
This study characterizes the costs of recommended initial HIV antiretroviral therapy regimens in the United States from 2012 to 2018 and the magnitude of cost changes over time.
This review summarizes 10 important research articles published in 2018 that address pediatric medical overuse.
This systematic review and meta-analysis of cohort and cross-sectional studies compares the diagnostic test accuracies of serum C-reactive protein level vs microbiological culture for diagnosing late-onset infection among newborn infants.
This prospective cohort study examines the association between seropositivity to Borrelia burgdorferi and incidental neuropsychiatric disorders and functional decline in rural southwestern France.
This registry-based cohort study examines the risk of serious infections associated with disease-modifying treatments for multiple sclerosis in Sweden.
This cohort study examines the frequency and clinical presentation of mucocutaneous disease due to Mycoplasma pneumoniae infection in children with community-acquired pneumonia.
A man in his 70s had an enlarging fleshy nodule of the right nasal conjunctiva and a foreign body sensation on his right eye for 2 weeks. The ophthalmologist prescribed a 3-week course of oral prednisone, but the lesion did not change in appearance. What is your diagnosis?
A 62-year-old man presents with subacute, painless vision loss in the right eye that developed over the course of 1 week, and a history of well-controlled type 2 diabetes and diffuse large B-cell lymphoma. What would you do next?
A 23-year-old man with Netherton syndrome presents with a history of herpes simplex keratitis and bacterial cultures positive for methicillin-resistant Staphylococcus aureus and Escherichia coli. What would you do next?
This case-control study examines the association of Listeria monocytogenes susceptibility with the receipt of daratumamab-based therapy in Canadian patients with multiple myeloma.
This cohort study assesses the association between cancer treatment and CD4 count and RNA levels in adults with human immunodeficiency virus.
This cross-sectional study investigates which features of a typical postfungal keratitis corneal scar are most associated with vision loss and evaluates the use of corneal imaging metrics as cornea-specific outcomes for clinical studies.
This nested case-control study examines the association of risk of infection with opioid use in immunocompromised patients.
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