Explore the latest in inflammatory bowel disease, including advances in the diagnosis and management of Crohn disease and ulcerative colitis.
This cohort study examines the association between physical fitness and subsequent risk for inflammatory bowel disease among children and adolescents in Taiwan.
This case series characterizes the clinical features and the clinical time course of TNF inhibitor–induced psoriasiform eruptions in children.
This randomized clinical trial compares clinical response at 12 weeks with olamkicept vs placebo in treating adult patients with active ulcerative colitis.
This cohort study examines all-cause and cause-specific mortality in patients with pyoderma gangrenosum.
This case report describes a patient with cutaneous intestinal metaplasia with invasive adenocarcinoma treated successfully with intralesional fluorouracil.
This mendelian randomization study investigates the associations between inflammatory bowel disease, particularly Crohn disease and ulcerative colitis, and psoriasis and psoriatic arthritis.
This comparative effectiveness study, conducted among a Danish nationwide cohort, compares the effectiveness and safety of vedolizumab vs tumor necrosis factor for older patients with inflammatory bowel disease (IBD).
This cohort study investigates the associated risk between new-onset psoriasis and tumor necrosis factor-α inhibitor treatment compared with nonbiologic conventional treatment.
A man aged 57 years with a history of Crohn disease presents to the emergency department after 3 weeks of bilateral periorbital pain and swelling. Computed tomography of the orbits reveals moderate bilateral lateral rectus muscle enlargement and mild enlargement of the left medial rectus muscle. What would you do next?
This meta-analysis evaluates the relative rate of cancer among patients with pediatric-onset inflammatory bowel disease (IBD).
This case report describes ulcerative plaques with ill-defined, violaceous, and undermined borders with cribriform scarring.
This randomized clinical trial assesses the effect of therapeutic drug monitoring vs standard therapy on sustained disease control without disease worsening among patients with immune-mediated inflammatory diseases (rheumatoid arthritis, spondyloarthritis, psoriatic arthritis, ulcerative colitis, Crohn disease, or psoriasis) undergoing maintenance therapy with infliximab.
This randomized trial assesses the effect of therapeutic drug monitoring vs standard therapy on clinical remission at 30 weeks among patients with immune-mediated inflammatory diseases (rheumatoid arthritis, spondyloarthritis, psoriatic arthritis, ulcerative colitis, Crohn disease, or psoriasis) initiating infliximab therapy.
This cohort study examines the association between use of anti–tumor necrosis factor (TNF) therapy or corticosteroids and all-cause mortality in a national cohort of veterans with inflammatory bowel disease (IBD).
This JAMA Insights Clinical Update reviews the diagnosis and management of anal fissures, including use of supportive, topical, injection, and surgical treatment options.
This review discusses the diagnosis and management of Crohn disease, including the importance of disease severity and risk stratification when determining a treatment strategy, the importance of maintenance therapy, and the adverse effects of treatment options.
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