Explore the latest in dyslipidemia, including recent guidelines for screening and use of statins, PCSK9 inhibitors, and other treatments.
This phase 1 randomized clinical trial evaluates the safety, tolerability, pharmacokinetics, and exploratory pharmacodynamic biomarker effects of muvalaplin in humans.
This randomized clinical trial investigates if evinacumab provides a sustained reduction in low-density lipoprotein cholesterol level in patients with hypercholesterolemia refractory to maximum-tolerated combinations of currently available lipid-lowering therapies.
This cohort study examines the risk of incident hypertension and statin initiation among adults starting pre-exposure prophylaxis with tenofovir alafenamide fumarate compared with propensity score–matched adults taking tenofovir disoproxil fumarate.
This cohort study evaluates outcomes of switching from soybean oil–based lipid emulsion to mixed-lipid emulsion parenteral nutrition in pediatric patients.
This post hoc analysis of the Randomized Comparison of Efficacy and Safety of Lipid Lowering With Statin Monotherapy vs Statin/Ezetimibe Combination for High-Risk Cardiovascular Disease (RACING) randomized clinical trial investigates if a moderate-intensity statin plus ezetimibe combination therapy is a feasible therapeutic option for patients with very high-risk atherosclerotic cardiovascular disease.
This Narrative Review assesses adenosine triphosphate citrate lyase inhibition with bempedoic acid as therapy in high-risk patients who require further low-density lipoprotein cholesterol lowering.
This systematic review and meta-regression evaluates the association between coronary plaque regression induced by lipid-lowering therapies and major adverse cardiovascular events.
This cohort study examines the association of childhood exposure to parental incarceration with cardiovascular risk among a nationally representative sample of US adults.
This cohort study estimates the projected reductions in rates of adverse events associated with coronary artery disease in a large US military veteran population when clinicians optimize oral lipid-lowering therapy as clinically appropriate.
This cross-sectional study examines the association of economic connectedness, social cohesion, and civic engagement with population health outcomes in all 50 US states.
This cross-sectional study investigates the health claims made on the labels of fish oil supplements and the total daily dose of eicosapentaenoic acid and docosahexaenoic acid in commonly available fish oil supplements.
This study of 13 540 individuals in Iceland (aged 40-75 years) evaluated the utility of protein risk scores for prediction of atherosclerotic cardiovascular disease events compared to risk prediction using polygenic risk scores in addition to risk scores based on clinical risk factors
This cross-sectional study evaluated the association between primary care practice use of electronic health record prompts, standing orders, and clinical registries and disparities by race and sex in practice-level care quality metrics consisting of aspirin use, blood pressure control, cholesterol management, and smoking cessation.
This cohort study aims to clarify the long-term trajectories of lipid-lowering, cardiovascular, and antidiabetic medication in patients who have undergone bariatric surgery compared with matched patients who received no surgery for morbid obesity.
This cohort study examines cardiovascular risk profiles, incident stroke, myocardial infarction, and mortality in US veterans with head and neck squamous cell carcinoma.
This systematic review and meta-analysis examines 20 clinical trials of various vegetarian diets for improved outcomes for patients with major cardiometabolic risk factors.
This JAMA Patient Page describes lipid disorders, and the pros and cons of screening for them in children and adolescents.
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