Explore the latest in melanoma, including advances in screening, prevention, diagnosis, and management of local and metastatic disease.
This systematic review examines the association of immune checkpoint inhibitor therapy with immune-related adverse effects, antitumor activity, and viral load in patients with HIV infection and advanced-stage cancer.
This case-control study assesses the risk factors for multiple primary melanomas in a cohort of patients with a histologically confirmed diagnosis of first melanoma.
This follow-up of a randomized phase 3 trial compares the 3-year survival with nivolumab vs that with dacarbazine in patients with previously untreated BRAF wild-type advanced melanoma.
A 41-year-old woman with stage IIa melanoma of the upper thigh presented with diffuse erythematous induration of the upper thigh expanding to the lower left abdominal area and palpable subcutaneous nodules on the ipsilateral gluteal region and leg during nivolumab therapy. What is your diagnosis?
This systematic review and meta-analysis examine randomized clinical trials to assess whether immunotherapy treatments for advanced cancer are less effective in female patients.
This study examines the preoperative and postoperative changes in quality of life as perceived and reported by patients who received surgical treatment for Tis or T1a melanoma of the head and neck.
This economic evaluation assesses the cost-effectiveness of talimogene laherparepvec plus ipilimumab combination therapy vs ipilimumab monotherapy in patients with advanced unresectable melanoma from the perspective of public and private US payers.
This population-based cohort study uses data from the Norwegian Women and Cancer study to investigate the association between phenotypic characteristics, pattern of UV radiation exposure, and risk of melanoma on different body sites.
This cohort study analyzes clinical records from 1980 to 2013 to identify rates of metastasis and survival in patients younger than 21 years with posterior uveal melanoma.
This study of 3 families, 1 from a clinical setting and 2 obtained from the GenoMEL Consortium, evaluated the association of the POT1 germline missense variant p.I78T with familial melanoma.
This case report describes the early diagnosis of skin melanoma metastasis by means of dermoscopy and confocal microscopy.
This case report describes an occurrence of herpetic whitlow following inadvertent inoculation with melanoma viral therapy
This multicenter cohort study examines the outcomes and risk for the development of subsequent cutaneous melanoma in moderately dysplastic nevi excisionally biopsied without residual clinical pigmentation but with positive histologic margins, observed for 3 years or more.
This secondary analysis of medical records assesses the specific risks of plaque-irradiated small choroidal melanoma on visual acuity and metastasis for small choroidal melanoma 3 mm thick or less.
The case report describes the occurrence of antiphospholipid syndrome following pembrolizumab treatment of stage IIIB unresectable melanoma.
This Insights discusses the necessity of completion node dissection after sentinel node biopsy in patients with melanoma.
This study examines the stochastic properties of primary uveal melanoma including the mutation rate as a function of tumor size and metastatic rate relative to the type of mutation
This exploratory recursive partitioning analysis modeled associations between prespecified covariates and survival outcomes using pooled data from 4 randomized clinical trials of adult patients with BRAF V600–mutated metastatic melanoma treated with dacarbazine, vemurafenib, or cobimetinib plus vemurafenib.
This economic analysis assesses the costs of use of the pigmented lesion assay vs visual and histopathologic assessment in model inputs of patients with primary pigmented lesions suggestive of melanoma.
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