Explore the latest in movement disorders from The JAMA Network, including Parkinson and Huntington disease, progressive supranuclear palsy, and essential tremor.
This Arts and Medicine essay explores the relevance of writer and artist William S. Burroughs to clinical medicine, and his importance to the author’s career as a Parkinson disease researcher.
This study examines the effect of LRRK2 risk variants on the age at onset of Parkinson disease.
This Viewpoint details the growing prevalance of Parkinson disease and outlines guiding efforts to help combat the pandemic.
This randomized clinical trial evaluates the effect of sodium oxybate in treatment of debilitating excessive daytime sleepiness and disturbed nighttime sleep in patients with Parkinson disease.
This study uses data from the Track and COHORT studies to examine an approach to planning prediagnosis clinical trials for Huntington disease.
This randomized clinical trial compares focused ultrasound thalamotomy with sham treatment for relieving tremor in patients with medication-refractory, tremor-dominant Parkinson disease.
This cohort study evaluates outcomes for patients treated with botulinum toxin applied to the buccinator muscle in the setting of facial synkinesis.
This population-based cohort study from the Rotterdam Study evaluates the association between cognitive function and risk of parkinsonism or Parkinson disease in participants who were free of parkinsonism and dementia.
This Viewpoint discusses the most recent advances in diagnosis of and treatment for Parkinson disease.
This cross-sectional study investigates the association between brain metabolism and motor scores of patients with early Huntington disease.
This randomized, double-blind, placebo-controlled clinical trial evaluates the efficacy and safety of extended-release ADS-5102 (amantadine) 274-mg capsules for treatment of levodopa-induced dyskinesia in patients with Parkinson disease.
This longitudinal observational study determines if the combination of smell identification testing followed by dopamine transporter imaging can accurately and efficiently identify individuals from the general population at risk for conversion to a clinical diagnosis of Parkinson disease.
This study examines the association of time of onset of autonomic dysfunction with disease progression and survival in Parkinson disease.
This open-label, single-arm study evaluates the safety and explores the efficacy of conversion from tetrabenazine to deutetrabenazine in patients with chorea associated with Huntington disease.
This population-based cohort study investigates the risk of mental disorders, specifically obsessive-compulsive disorder and tic disorders, after a streptococcal throat infection.