Movement Disorders

This cohort study attempts to examine the longitudinal association of frailty phenotype with the development of Parkinson disease and to explore the modification role of genetic risk of Parkinson disease in such association.

This case report describes noncontiguous overflow dystonia in a patient with diabetes, hypertension, and a history of left putaminal hemorrhage and right hemiparesis.

In this case report, a patient with Tourette syndrome was admitted to the emergency department with nonrhythmic, continuous, generalized hyperkinetic movements associated with muscle contractions in the trunk, neck, and upper and lower limbs caused by depletion of the deep brain stimulation battery.

This case-control study investigates the risk factors, comorbidities, and prodromal symptoms associated with a diagnosis of Parkinson disease in a large representative database.

This Viewpoint discusses the current lack of evidence of functional neuroimaging affecting patient outcomes in parkinsonian conditions.

This Viewpoint makes a case for changing the approach in Parkinson disease research efforts from one of proteinopathy (accrual of amyloids) to proteinopenia (depletion of normal proteins).

This case-control study uses Medicare-linked data from the National Health and Aging Trends Study to examine whether limitations in daily functioning existed in the 3 years before a diagnosis of Parkinson disease in a sample of Medicare beneficiaries.

This case-control study investigates the association between antiepileptic drugs and incident Parkinson disease.

This Viewpoint discusses the degree to which Parkinson disease vs repetitive boxing-related head trauma contributed to Muhammad Ali’s progressive motor and cognitive impairments.

This case report describes the optic nerve features of a male patient aged 23 years with a diagnosis of autosomal recessive spastic ataxia of Charlevoix-Saguenay.

This Viewpoint advocates for careful consideration in the timing of physical therapy for individuals with Parkinson disease as a possible avenue toward improved outcomes.

This randomized clinical trial evaluates whether simvastatin has potential as a disease-modifying treatment for patients with moderate Parkinson disease.

This case series assesses the levels of levodopa in Mucuna pruriens supplements available in the US that are included in the National Institutes of Health Dietary Supplement Label Database.