Explore the latest in demyelinating disorders, including the etiology, diagnosis, and management of multiple sclerosis and neuromyelitis optica.
This Viewpoint encourages using the deliberative model in treating and communicating with patients with relapsing-remitting multiple sclerosis.
This study evaluates the extent to which the US Centers for Disease Control and Prevention case definition of acute flaccid myelitis incorporates possible alternative diagnoses.
This cohort study investigates whether serostatus of autoantibodies targeting myelin oligodendrocyte glycoprotein (transient vs persistent) and titer change over time provide clinical utility in predicting the likelihood of relapse in patients after acute disseminated encephalomyelitis.
This cohort study examines the association of superimposed relapses in progressive-onset multiple sclerosis on disease outcomes.
This study evaluates the diagnostic accuracy of the 2017 McDonald criteria vs the 2010 criteria to predict clinically definite multiple sclerosis in patients with a typical clinically isolated syndrome.
This case report describes a patient aged in the mid-20s with a unique sequel to a genetically established case of Leber hereditary optic neuropathy.
This systematic review and meta-analysis of 17 randomized clinical trials including 3161 patients examines the association of efficacy and tolerability of cannabinoids with spasticity, pain, and bladder dysfunction in patients with multiple sclerosis (MS).
This cohort study assesses the dynamics of brain volume loss after multiple sclerosis onset and evaluates the repeatability of brain volume loss estimates made via 2 magnetic resonance imaging protocols.
This longitudinal cohort study investigates the association of retinal optical coherence tomographic results with future disease activity in patients with clinically isolated syndrome.
This Viewpoint summarizes the current knowledge of the clinical, radiologic, and immunologic features of adult patients who are positive for anti–myelin oligodendrocyte glycoprotein and compares these individuals with patients with multiple sclerosis and patients with neuromyelitis optica.
This review discusses the current state of evidence for the role that vitamins and dietary supplements play in multiple sclerosis and its animal models, with an emphasis on recent studies, and addresses biological plausibility and safety issues.
This Viewpoint discusses the validity of using a strategy of targeting no evident disease activity to treat relapsing multiple sclerosis.
This randomized clinical trial assesses whether the administration of high-dose intravenous corticosteroid is superior to a bioequivalent oral corticosteroid dose for the treatment of patients with acute optic neuritis.
This case report describes a patient with relapsing-remitting multiple sclerosis treated with dimethyl fumarate who developed Listeria monocytogenes infection complicated by rhombencephalitis.
This multinational cohort study examines the clinical phenotypes, treatment responses, and outcomes of children with relapsing myelin oligodendrocyte glycoprotein antibody–associated disease.
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