Explore the latest in nail disorders, including nail changes as signs of systemic disease and drug reactions.
This survey study examines the prevalence and characteristics of itch in pachyonychia congenita.
This case report describes opaque trachyonychia of all fingernails.
This case series documents the incidence of various nail changes as sequalae to Stevens-Johnson syndrome/toxic epidermal necrolysis.
A 70-year-old man with a 2-year history of nasal congestion, rhinorrhea, and chronic cough developed yellow discoloration and thickening of his fingernails and toenails and progressive exertional dyspnea and edema of both lower extremities. ANA was positive (1:160, nucleolar pattern), a chest radiograph was unrevealing, and sinus CT showed bilateral maxillary and posterior ethmoidal sinusitis. What is the diagnosis and what would you do next?
This case report describes a young man with Bart-Pumphrey syndrome, a rare genetic disorder affecting both the skin of the hands and the hearing.
A girl younger than 2 years presented with a 7-month history of an inflammatory plaque with a central shiny orange crust on her left index finger and no improvement with empiric therapy. What is your diagnosis?
This cohort study examines the association between use of oral or topical terbinafine and malformations and spontaneous abortions in women who receive terbinafine during pregnancy.
This case report describes an 8-year-old girl who presented with a linear pigmented band on the nail of her right middle finger.
This study assesses the rate and utility of monitoring laboratory test result abnormalities in adults and children taking terbinafine and griseofulvin for treatment of dermatophyte infections.
This systematic review summarizes evidence on the effectiveness and safety of current cryotherapy methods to prevent hair, skin, and nail changes associated with chemotherapy.
A man in his 40s presented to the dermatology clinic for evaluation of a dark brown longitudinal pigment band covering his left second toenail; the lesion appeared 12 months prior, had been growing, and was asymptomatic. What is your diagnosis?
This case report describes the occurrence of onychomadesis in a patient following a fish pedicure.
This cohort study identifies the dermoscopic features of subungual melanoma in situ in a Korean population and assesses a predictive scoring model that distinguishes the diagnosis of subungual melanoma in situ from longitudinal melanonychia in patients with pigmented nails.
This secondary analysis of 2 randomized clinical trials evaluates the effect of guselkumab vs adalimumab or placebo on psoriasis in specific difficult-to-treat body regions.
This article argues that the physical examination finding of long toenails should alert the clinician to other possible care needs and help guide questions as to the underlying differential diagnosis of the untrimmed toenails.
A woman receiving immunosuppressant therapy after a prior kidney transplant presented with a tender ulcerated nodule on her fingernail with nail loss, purulent drainage, and histopathology showing a pyogenic granuloma–like response with atypical epithelioid and spindled cells adjacent to blood vessels. What would you do next?
This Clinical Evidence Synopsis summarizes a Cochrane review comparing the effectiveness and safety of oral antifungal medications for treatment of fungal toenail infection.
This study evaluated the efficacy and tolerability of topical timolol, 0.5%, gel as a treatment of paronychia and pseudopyogenic granuloma induced by antineoplastic agents.
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