Explore the latest in nephrology, including recent guidelines and advances in the prevention and management of acute kidney injury and CKD.
This randomized clinical trial examines whether patients treated with sunitinib before cytoreductive nephrectomy have better outcomes than patients immediately treated with cytoreductive nephrectomy and then given sunitinib.
This randomized, open-label, blinded end point randomized clinical trial examined the effect of oral alfacalcidol, a vitamin D receptor activator, on cardiovascular events in patients with cardiovascular kidney disease receiving hemodialysis.
Following esophageal resection for cancer, a 73-year-old man was admitted to the ICU with pneumonia and progressive acute respiratory failure, and he was placed on mechanical ventilation. At day 5, his creatinine level continued to increase. How would you proceed?
This cohort study evaluates the association of adherence and treatment intensity with cardiovascular outcomes in patients with documented cardiovascular disease, type 2 diabetes without cardiovascular disease or chronic kidney disease, and chronic kidney disease without cardiovascular disease.
This cohort study examines the prevalence of benign pathologic findings among adults after partial nephrectomy and potential risk factors associated with this prevelence.
This before-after study examines changes in 1-year mortality among nonelderly patients initiating dialysis in states that did vs did not participate in Medicaid expansion under the Affordable Care Act in 2014.
This study uses data from the Alberta Kidney Disease Network population database to evaluate the association of angiotensin-converting enzyme inhibitor or angiotensin receptor blocker use with posthospitalization outcomes in patients with acute kidney injury.
This Viewpoint highlights the challenges faced by patients with end-stage renal disease who are homeless, recommends measures to determine the prevalence and outcomes of homelessness among Medicare beneficiaries with end-stage renal disease, and proposes approaches to improve outcomes through supportive housing.
This analysis of Global Burden of Disease 2016 study data and methodologies describes the change in burden of chronic kidney disease at the US state level from 2002 to 2016.
This cohort study compares 9 markers of patient complexity among patients treated by physicians in different specialties in Alberta, Canada, using data collected by the province’s universal health care system.
This cohort study examines inpatient, emergency department, and outpatient data to assess the risk of urologic or nonurologic cancer among Danish adults with hematuria first diagnosed at the hospital.
This narrative review discusses the rationale and results of clinical trials in immunotherapy-based combination therapy for patients with advanced renal cell carcinoma.
This randomized clinical trial determines the optimal therapeutic dose, effect on kidney function, and adverse effects of human recombinant alkaline phosphatase in patients who are critically ill with sepsis-associated acute kidney injury.
This randomized clinical trial compares the effect of adding the somatostatin analogue lanreotide to standard care vs standard care alone on change in estimated glomerular filtration rate (eGFR) in patients with autosomal dominant polycystic kidney disease (PCKD).
This Viewpoint discusses the retention of gadolinium, used in contrast-enhanced MRI, in skin and kidney tissue and the efforts of experts from radiological societies, the NIH, and the FDA to study the safety of this element in clinical use.
This randomized clinical trial compares the effects of the dipeptidyl peptidase 4 inhibitor linagliptin vs placebo plus usual care on cardiovascular (CV) and renal outcomes in adults with type 2 diabetes and high CV and renal risk.
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