Explore the latest in neuro-oncology, including advances in diagnosis and management of glial tumors, CNS lymphomas, and CNS metastases.
This case series examines susceptibility-weighted imaging in patients who had intravascular lymphoma of the central nervous system.
A 17-year-old girl presented with 3 months of decreased vision in the right eye associated with throbbing pain with eye movement. Magnetic resonance imaging revealed a fusiform expansion of the right optic nerve and enhancement of the orbital, canalicular, and prechiasmatic segments of the right optic nerve. What would you do next?
A patient with chronic myelogenous leukemia presented with blurry vision and peripapillary intraretinal and preretinal hemorrhages obscuring the optic disc margins of both eyes. What would you do next?
This cohort study assesses the clinical activity and toxic effects of cabozantinib to treat brain metastases in patients with metastatic renal cell carcinoma.
This randomized clinical trial examines the use of carboplatin and isotretinoin in children with high-risk medulloblastoma, with subgroup analysis by molecular classification.
This diagnostic study compares the sensitivity and accuracy for detecting leptomeningeal disease via genomic sequencing of cell-free DNA with that of cytologic assessment of cerebrospinal fluid obtained from patients with suspected or cytologically confirmed leptomeningeal disease.
This Viewpoint discusses the challenges and potential benefits of including patients with active central nerve system metastases in clinical trials that evaluate cancer drugs.
This cohort study examines the association of targeted therapy and intracranial metastatic disease with patient survival.
This case report describes a woman with a rare bilateral case of primary central nervous system lymphoma.
This cohort study determines the proportion of phase 3 clinical trials for patients with metastatic breast cancer, lung cancer, and melanoma that included patients with brain metastases and/or evaluated central nervous system–specific end points.
This cohort study used registry data to assess outcomes in patients with primary central nervous system lymphoma undergoing autologous hematopoietic cell transplant with commonly used conditioning regimens.
This study evaluates residual fatigue and cognitive defects in patients after leucine-rich glioma-inactivated 1 antibody encephalitis.
These case reports investigate the potential association between BRAF inhibitors and conjunctival plaques in patients with pediatric brain tumor.
This Viewpoint advocates for a reevaluation of the use of temozolomide for patients with MGMTp unmethylated glioblastomas during the COVID-19 pandemic.
This case report describes a 73-year-old man who presented with intractable hiccups and lymphoplasmacytic lymphoma.
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