Explore the latest in neuro-oncology, including advances in diagnosis and management of glial tumors, CNS lymphomas, and CNS metastases.
This secondary analysis of a randomized clinical trial examines the association of modern chemoradiotherapy with survival among patients with stage I to II small cell lung cancer compared with that among patients with stage III small cell lung cancer.
This cohort study investigates the association between radiation doses in the parotid glands and self-reported xerostomia among adults treated with whole-brain radiation therapy.
This exploratory secondary analysis of a randomized clinical trial evaluated local control of brain metastases among patients treated with stereotactic radiosurgery vs surgical resection in the European Organization for the Research and Treatment of Cancer 22952-26001 phase 3 trial.
This Viewpoint discusses the role of prophylactic cranial irradiation in small cell lung cancer in the current setting of active surveillance via magnetic resonance imaging.
This secondary analysis of the NRG Oncology/RTOG 0424 randomized clinical trial examines the proportion of patients with MGMT promoter methylation and its association with survival outcomes in high-risk glioma treated with radiotherapy and temozolomide.
Using 14 years of data from the US Central Brain Tumor Registry and the Surveillance, Epidemiology, and End Results registries, this study examines the incidence and survival rates of glioma and its subtypes among 4 racial or ethnic groups.
This clinical trial investigates the maximum tolerated dosage of tucatinib combined with ado-trastuzumab emtansine in the treatment of patients with ERBB2/HER2-positive metastatic breast cancer with and without brain metastases.
This study investigates the association between immunotherapy and symptomatic radiation necrosis in patients with melanoma, non–small-cell lung cancer, or renal cell carcinoma and newly diagnosed brain metastases treated with stereotactic radiation therapy.
This cohort study evaluates the association of cerebrospinal fluid biomarkers of brain injury with short- and long-term outcomes and genetic polymorphisms in children receiving chemotherapy for acute lymphoblastic leukemia.
This study analyzes the value of magnetic resonance imaging of the brain for patients with cancers that frequently metastasize to the brain.
This secondary analysis of a randomized clinical trial examines the association between therapy with tumor-treating fields plus temozolomide and survival and health-related quality of life in patients with glioblastoma after completion of chemoradiotherapy.
This case report describes the presentation of Lhermitte-Duclos disease and its association with Cowden disease.
An adolescent boy presented with cognitive and behavioral changes, headaches, and progressively worsening weakness of the left arm and leg. On magnetic resonance imaging, a lesion in the right basal ganglia discovered 16 months previously appeared larger. What is your diagnosis?
This review reports the ablative and nonablative applications of transcranial focused ultrasound for neurological conditions.
This randomized trial compares the effects of tumor-treating fields plus temozolomide vs temozolomide alone on progression-free and overall survival in patients with glioblastoma who had undergone resection or biopsy and radiochemotherapy.
This study presents a genetic locus for intracranial arachnoid cysts.
This case series describes the clinical presentation of optic nerve infiltration, its imaging characteristics, and outcomes in patients with primary central nervous system lymphomas.
This study analyzes Medicare claims data associated with end-of-life hospitalization care and costs for elderly patients with a malignant brain tumor.
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