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    Neuro-ophthalmology

    Explore the latest in neuro-ophthalmology, including optic neuropathies and systemic diseases affecting oculomotor and visual function.

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    • Morning Glory Syndrome With Bergmeister Papilla and Retinal Detachment
      JAMA Ophthalmology
      Case Report
      February 16, 2023

      This case report discusses a diagnosis of morning glory syndrome and concurrent Bergmeister papilla and retinal detachment in a child aged 3 years.

      Ophthalmology Retinal Disorders Ophthalmic Images Pediatrics Congenital Defects
      Full Text | pdf link PDF | CME & MOC is active quiz
    • Silicone Oil Droplet Over the Optic Nerve Head After Intravitreal Injections
      JAMA Ophthalmology
      Case Report
      February 16, 2023

      This case report discusses the finding of a silicone oil droplet over the optic nerve head of a patient with a history of multiple intravitreal injections.

      Ophthalmology Retinal Disorders Ophthalmic Images Clinical Pharmacy and Pharmacology Neurology
      Full Text | pdf link PDF | CME & MOC is active quiz
    • Incidence and Progression of Chorioretinal Folds During Long-Duration Spaceflight
      JAMA Ophthalmology
      Research
      February 1, 2023

      This cohort study assesses the incidence and presentation of chorioretinal folds in long-duration International Space Station crew members and objectively quantifies the progression of choroidal folds during spaceflight.

      Ophthalmology Choroidal Disorders Retinal Disorders Neurology
      Full Text | pdf link PDF
    • Spaceflight-Associated Neuro-Ocular Syndrome and Increased Intracranial Pressure—Are We Closer to Understanding the Relationship?
      JAMA Ophthalmology
      Opinion
      February 1, 2023
      Neurology Ophthalmology
      Full Text | pdf link PDF
    • Diagnostic Optic Nerve Features in Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay
      JAMA Neurology
      Case Report
      January 1, 2023

      This case report describes the optic nerve features of a male patient aged 23 years with a diagnosis of autosomal recessive spastic ataxia of Charlevoix-Saguenay.

      Neurogenetics Neurology Ophthalmic Imaging Movement Disorders Spinal Cord Disorders
      Full Text | pdf link PDF | CME & MOC is active quiz
    • Identification of Factors Associated With the Development of Optic Disc Edema During Spaceflight
      JAMA Ophthalmology
      Research
      December 1, 2022

      This cohort study assesses whether associations exist between the development of optic disc edema during long spaceflights and crowded optic nerve head morphology and other factors.

      Neurology Ophthalmology
      Full Text | pdf link PDF
    • Possible Mitigating Factors in Optic Disc Edema During Spaceflight
      JAMA Ophthalmology
      Opinion
      December 1, 2022
      Neurology Ophthalmology Environmental Health
      Full Text | pdf link PDF
    • Ophthalmological Findings in Youths With a Newly Diagnosed Brain Tumor
      JAMA Ophthalmology
      Research
      October 1, 2022

      This cohort study assesses the prevalence and types of visual symptoms and abnormal ophthalmological findings in Dutch youths with a newly diagnosed brain tumor.

      Pediatric Cancer Neuro-oncology Oncology Ophthalmology Pediatrics
      Full Text | pdf link PDF
    • Risk of Ocular Adverse Events With Taxane-Based Chemotherapy
      JAMA Ophthalmology
      Research
      September 1, 2022

      This study aims to quantify the risk of epiphora, cystoid macular edema, and optic neuropathy with taxane-based chemotherapy agents by undertaking a large pharmacoepidemiologic study.

      Oncology Pharmacoepidemiology Ophthalmology External Eye Disease Breast Cancer
      Full Text | pdf link PDF
    • Diplopia and Ptosis in an Older Woman
      JAMA Neurology
      Case Report
      September 1, 2022

      A 75-year-old woman presented with a 3-day history of progressive headache, right-sided ptosis, and binocular diplopia. She had normal visual acuity and an unremarkable dilated fundus examination. Laboratory results revealed an elevated C-reactive protein and erythrocyte sedimentation rate. What is your diagnosis?

      Neurology Ophthalmology Rheumatology Clinical Challenge Geriatrics
      Full Text | pdf link PDF | CME & MOC is active quiz
    • Analysis of Pregnancy-Related Attacks in Neuromyelitis Optica Spectrum Disorder: A Systematic Review and Meta-Analysis
      JAMA Network Open
      Research
      August 4, 2022

      This systematic review and meta-analysis assesses factors associated with pregnancy-related be increased in the postpartum period of neuromyelitis attacks, annualized relapse rate, and Expanded Disability Status Scale score in each phase of pregnancy among patients with NMOSD.

      Neurology Pregnancy Obstetrics Obstetrics and Gynecology Neuromyelitis Optica
      Full Text | pdf link PDF open access
    • Changes in Optic Nerve Head and Retinal Morphology During Spaceflight and Acute Fluid Shift Reversal
      JAMA Ophthalmology
      Research
      August 1, 2022

      This cohort study investigates changes in optic nerve head and retinal morphology during spaceflight and brief in-flight exposure to lower-body negative pressure.

      Neurology Ophthalmology
      Full Text | pdf link PDF
    • Livedo Reticularis—A Presenting Sign of Neuromyelitis Optica Spectrum Disorder
      JAMA Neurology
      Case Report
      August 1, 2022

      This case report describes a man aged 58 years who presented with intermittent chest pain, numbness and tingling of the upper extremities, and a violaceous, reticular rash on his lower extremities, abdomen, and flank.

      Dermatology Images in Neurology Demyelinating Disorders Neurology Ophthalmology
      Full Text | pdf link PDF | CME & MOC is active quiz
    • Bilateral Papilledema and Intact Vision With Normal Intracranial Pressure
      JAMA Ophthalmology
      Case Report
      July 1, 2022

      A 23-year-old woman presented with 6 months of intermittent bilateral retro-orbital pain associated with blurred vision and wavy lines in the vision of both eyes, followed by worsening numbness and tingling of her hands and legs. Ophthalmoscopic examination revealed blurring and elevation of the nasal margins of the optic disc consistent with grade 1 optic disc edema in both eyes. What would you do next?

      Hematology Neurology Hematologic Cancer Clinical Challenge Ophthalmology
      Full Text | pdf link PDF | CME & MOC is active quiz
    • Progressively Worsening Unilateral Ptosis in a Woman in Her 60s
      JAMA Ophthalmology
      Case Report
      June 1, 2022

      A woman in her 60s with a history of hyperlipidemia, hypothyroidism, and chronic migraines presented with progressively worsening left-sided ptosis. Examination revealed mild fullness in the left superior sulcus and mildly increased left-sided resistance to retropulsion. What would you do next?

      External Eye Disease Oncology Ophthalmology Lymphomas Clinical Challenge
      Full Text | pdf link PDF | CME & MOC is active quiz
    • Sudden-Onset Headache and Binocular Vertical Diplopia in a Young Patient
      JAMA Ophthalmology
      Case Report
      June 1, 2022

      A 24-year-old woman was experiencing sudden onset of headache, nausea, and binocular vertical diplopia. There was minimal limitation in infraduction in the left eye with corresponding left hypertropia, while ophthalmoscopy and visual field findings were normal in both eyes. What would you do next?

      Endocrinology Ophthalmology Radiology Diabetes and Endocrinology Neuroimaging
      Full Text | pdf link PDF | CME & MOC is active quiz has multimedia
    • Papilledema in an Adolescent With Anemia and Leukopenia
      JAMA Ophthalmology
      Case Report
      May 1, 2022

      A 12-year-old girl with anemia and no ocular history presents with normal visual acuity and floaters in her right eye. Dilated eye examination reveals bilateral optic disc edema, magnetic resonance imaging shows diffuse signal abnormality in the bone marrow, and opening pressure on lumbar puncture is elevated. What would you do next?

      Oncology Ophthalmology Hematologic Cancer Leukemias Clinical Challenge
      Full Text | pdf link PDF | CME & MOC is active quiz
    • Ptosis With Fluctuating Diplopia
      JAMA Ophthalmology
      Case Report
      May 1, 2022

      A patient in their 60s had a 2-month history of new-onset fluctuating diplopia and worsening right upper eyelid ptosis that did not improve after ptosis repair. What would you do next?

      Ophthalmology Carotid and Intracranial Artery Disease Clinical Challenge
      Full Text | pdf link PDF | CME & MOC is active quiz
    • Video-Oculography to Guide Neuroimaging for Dizziness and Vertigo
      JAMA Otolaryngology–Head & Neck Surgery
      Opinion
      May 1, 2022
      Neurology Ophthalmology Otolaryngology Otology Radiology
      Full Text | pdf link PDF
    • Cystic Lesion of the Optic Nerve in an Asymptomatic Adult Woman
      JAMA Ophthalmology
      Case Report
      April 21, 2022

      This case report describes a diagnosis of central retinal artery aneurysm of the left optic nerve head in a woman aged 54 years who presented with an asymptomatic cystic lesion in the left eye.

      Neurology Ophthalmology Ophthalmic Images Retinal Disorders
      Full Text | pdf link PDF | CME & MOC is active quiz
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