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    Neuropathy

    Explore the latest in neuropathies, including diagnosis and management of patients with hereditary, acquired, and idiopathic forms.

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    • What Is Guillain-Barré Syndrome?
      JAMA
      Patient Information
      February 21, 2023

      This JAMA Patient Page describes the autoimmune disease Guillain-Barré syndrome and its risk factors, diagnosis, treatment, and prognosis.

      Demyelinating Disorders Neurology Patient Information JAMA Patient Information
      Full Text | pdf link PDF free
    • Cost-effectiveness of Novel Macrophage-Regulating Treatment for Wound Healing in Patients With Diabetic Foot Ulcers From the Taiwan Health Care Sector Perspective
      JAMA Network Open
      Research
      January 12, 2023

      This economic evaluation assesses the cost-effectiveness of an ON101 cream added on to general wound care vs general wound care alone for diabetic foot ulcers (DFUs) from the Taiwan health care sector perspective.

      Diabetes and Endocrinology Drug Development Health Care Economics, Insurance, Payment Diabetes Wound Care, Infection, Healing
      Full Text | pdf link PDF open access
    • Noninferiority of Posterior Cervical Foraminotomy vs Anterior Cervical Discectomy With Fusion for Procedural Success and Reduction in Arm Pain Among Patients With Cervical Radiculopathy at 1 Year: The FACET Randomized Clinical Trial
      JAMA Neurology
      Research
      January 1, 2023

      This randomized clinical trial evaluates the noninferiority of posterior surgery to anterior surgery for outcomes in patients with cervical radiculopathy at 1 year.

      Neurology Spinal Cord Disorders Pain Medicine Orthopedics
      Full Text | pdf link PDF
    • How SAFE Is Real-world Use of Spinal Cord Stimulation Therapy for Chronic Pain?
      JAMA Neurology
      Opinion
      January 1, 2023
      Neurology Pain Medicine
      Full Text | pdf link PDF
    • Types and Concentrations of Blood-Based Biomarkers in Adults With Peripheral Neuropathies: A Systematic Review and Meta-analysis
      JAMA Network Open
      Research
      December 27, 2022

      This systematic review and meta-analysis assesses blood-based biomarker concentrations associated with nerve involvement in patients with peripheral neuropathy compared with control participants.

      Neurology Pathology and Laboratory Medicine Neuromuscular Diseases
      Full Text | pdf link PDF open access
    • Abdominal Pain in a 15-Year-Old Adolescent Girl
      JAMA
      Case Report
      December 20, 2022

      A 15-year-old adolescent girl taking an oral contraceptive had 3 days of pain in a 1-cm area of the lower left abdominal quadrant. She had no nausea/vomiting, diarrhea, hematochezia, bloating, or anorexia; no precipitating factors for the pain; and no history of pregnancy, abdominal surgery, or abdominal trauma. Results from laboratory tests, endoscopy, and abdominal computed tomography were normal. What is the diagnosis and what would you do next?

      Emergency Medicine Neuromuscular Diseases Surgery Clinical Challenge Gastroenterology and Hepatology
      Full Text | pdf link PDF | CME & MOC is active quiz
    • Association of Taxane Type With Patient-Reported Chemotherapy-Induced Peripheral Neuropathy Among Patients With Breast Cancer
      JAMA Network Open
      Research
      November 2, 2022

      This cohort study compares the symptom spectrum of patient-reported chemotherapy-induced peripheral neuropathy associated with nab-paclitaxel, paclitaxel, and docetaxel treatments among patients with breast cancer.

      Oncology Women's Health Pharmacy and Clinical Pharmacology Breast Cancer Clinical Pharmacy and Pharmacology
      Full Text | pdf link PDF open access
    • Neurogenic Unilateral Leg Edema
      JAMA Neurology
      Case Report
      November 1, 2022

      This case report describes neurogenic unilateral leg edema that was a consequence of chronic regional pain syndrome induced by an S1 radiculopathy.

      Anesthesiology Neurology Pain Medicine Images in Neurology
      Full Text | pdf link PDF | CME & MOC is active quiz
    • Effect of Spinal Cord Burst Stimulation vs Placebo Stimulation on Disability in Patients With Chronic Radicular Pain After Lumbar Spine Surgery: A Randomized Clinical Trial
      JAMA
      Research
      October 18, 2022

      This placebo-controlled, crossover randomized clinical trial compares the effects of spinal cord burst stimulation vs placebo stimulation in patients with chronic radiculopathy after surgery for degenerative lumbar spine disorders.

      Surgery Spinal Cord Disorders Pain Medicine Orthopedics Medical Devices and Equipment
      Full Text | pdf link PDF
    • Risk of Guillain-Barré Syndrome Among Older Adults Receiving Influenza Vaccine in Taiwan
      JAMA Network Open
      Research
      September 21, 2022

      This cross-sectional study investigates the association between seasonal influenza vaccination and incidence of Guillain-Barré syndrome among adults 65 years or older in Taiwan.

      Public Health Vaccination Infectious Diseases Influenza Demyelinating Disorders
      Full Text | pdf link PDF open access
    • Evaluation of Gabapentin and Transforaminal Corticosteroid Injections for Brachioradial Pruritus
      JAMA Dermatology
      Research
      September 1, 2022

      This case series compares the reported outcomes of transforaminal injections and oral medications in patients with a brachioradial pruritus diagnosis.

      Dermatology Neurology
      Full Text | pdf link PDF
    • Association Between a Distinctive Autoantibody-Associated Brainstem Sensory Syndrome and Immune Checkpoint Inhibitors
      JAMA Neurology
      Research
      September 1, 2022

      This case series investigates the association of a segmental, facial, antibody-associated brainstem sensory syndrome with the immune checkpoint inhibitor pembrolizumab.

      Facial Nerve Facial Plastic Surgery Neurology Targeted and Immune Cancer Therapy Oncology
      Full Text | pdf link PDF
    • What Is Carpal Tunnel Syndrome?
      JAMA
      Patient Information
      August 9, 2022

      This JAMA Patient Page describes carpal tunnel syndrome and its symptoms, risk factors, diagnosis, and treatment options.

      Neurology Orthopedics Patient Information JAMA Patient Information
      Full Text | pdf link PDF free has multimedia
    • Chemotherapy-Induced Peripheral Neuropathy
      JAMA Internal Medicine
      Opinion
      July 1, 2022

      This Teachable Moment describes a man in his 70s with stage III colon cancer who presented with sensory symptoms after undergoing chemotherapy and was diagnosed with chemotherapy-induced peripheral neuropathy.

      Oncology Teachable Moment Adverse Drug Events Neurology
      Full Text | pdf link PDF | CME & MOC is active quiz
    • Gabapentin Increasingly Implicated in Overdose Deaths
      JAMA
      News
      June 28, 2022
      Clinical Pharmacy and Pharmacology Neurology Toxicology Pharmacoepidemiology Public Health
      Full Text | pdf link PDF
    • Common Hand Conditions: A Review
      JAMA
      Review
      June 28, 2022

      This Review summarizes problems with the hands, wrists, and fingers that are commonly encountered in primary care, including carpal tunnel syndrome and arthritis, among others, and offers a range of treatment options for each.

      Trauma and Injury Geriatrics Osteoarthritis Rheumatology Orthopedics
      Full Text | pdf link PDF | CME & MOC is active quiz has multimedia
    • The Global Burden of Polyneuropathy—In Need of an Accurate Assessment
      JAMA Neurology
      Opinion
      June 1, 2022

      This Viewpoint discusses the patient morbidity and global financial health care cost of polyneuropathy.

      Neurology Neuromuscular Diseases
      Full Text | pdf link PDF
    • New Insights Into Sensory Impairment and Dementia Risk
      JAMA Network Open
      Opinion
      May 5, 2022
      Geriatrics Neurology Dementia and Cognitive Impairment Neuromuscular Diseases
      Full Text | pdf link PDF open access
    • Painful Neck Lump in a Patient 10 Years After Parotidectomy
      JAMA Otolaryngology–Head & Neck Surgery
      Case Report
      May 1, 2022

      A 63-year-old man presents with a history of previous left superficial parotidectomy 10 years before for a Warthin tumor and pain at the operative site of 6 months’ duration. What is your diagnosis?

      Otolaryngology Head and Neck Surgery Pain Medicine Clinical Challenge Neurology
      Full Text | pdf link PDF
    • Association of Race, Ethnicity, and Rurality With Major Leg Amputation or Death Among Medicare Beneficiaries Hospitalized With Diabetic Foot Ulcers
      JAMA Network Open
      Research
      April 21, 2022

      This cohort study assesses whether intersecting identities of Black race, ethnicity, rural residence, or living in a disadvantaged neighborhood are associated with increased risk in major leg amputation or death among Medicare beneficiaries hospitalized with diabetic foot ulcers.

      Health Disparities Surgery Health Inequities Orthopedics Equity, Diversity, and Inclusion
      Full Text | pdf link PDF open access
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