Explore the latest in neurosurgery, including recent advances in surgical management of epilepsy, CNS tumors, spinal disorders, and more.
This randomized clinical trial compares the effects of prophylactic hypothermia targeted to a core temperature of 33°C-35°C vs usual normothermic emergency care on neurologic outcomes or independent living of adult patients with severe traumatic brain injury (TBI).
This cohort study examines the association of seizure spread with seizure recurrence after surgery in patients who underwent medial temporal resections for drug-resistant temporal lobe epilepsy.
This cohort study describes the efficacy and safety of internal globus pallidus deep brain stimulation in Filipino patients with severe X-linked dystonia parkinsonism and predominant dystonia.
This medical record review described a unique pattern of spinal cord gadolinium enhancement on magnetic resonance imaging in patients with spinal dural arteriovenous fistulas.
This systematic review and meta-analysis of randomized clinical trials assesses the risk of intracranial hemorrhage with non–vitamin K antagonist oral anticoagulant use compared with aspirin use.
This Viewpoint discusses the application of precision medicine to neurocritical care, providing an overview of what has worked in the past to define a framework for advancing precision medicine more broadly in neurocritical care
This study of a case series of 4 patients investigates the safety and efficacy of deep brain stimulation for obesity associated with Prader-Willi syndrome.
This narrative review discusses the limits of current cerebral cavernous malformation treatment and introduces findings from in vitro and in vivo studies that provide insight into cerebral cavernous malformation pathogenesis and indicate molecular mechanisms as potential therapeutic targets.
This exploratory secondary analysis of a randomized clinical trial evaluated local control of brain metastases among patients treated with stereotactic radiosurgery vs surgical resection in the European Organization for the Research and Treatment of Cancer 22952-26001 phase 3 trial.
This Viewpoint discusses genetic models of trigeminal neuralgia pathogenesis.
This Viewpoint presents temporal interference stimulation, an optimized alternative to deep brain stimulation, transcranial magnetic stimulation, and transcranial electrical stimulation.
This randomized clinical trial evaluates the safety and efficacy of atrovastatin as a nonsurgical alternative for treating Chinese patients with chronic subdural hematoma.
This cohort study uses data from the National Surgical Quality Improvement Project and a nationally representative sample of Medicare beneficiaries to examine how often after surgical evacuation nontraumatic subdural hematoma reaccumulates and necessitates repeated operation among older US adults.
A 74-year-old man taking rivaroxaban for atrial fibrillation developed a subdural hematoma and had an elevated prothrombin time (PT) with normal activated partial thromboplastin time (aPTT) and platelets prior to planned surgical evacuation. How do you interpret the results?
This registry-based multicenter cohort study examines long-term survival after carotid endarterectomy (CEA) and carotid artery stenting (CAS) in real-world practice using a novel instrumental variable method designed for time-to-event outcomes compared with traditional risk-adjustment models used in observational studies for survival analyses.
This Viewpoint suggests approaches to scaling up neurosurgery in low- and middle-income countries for patients with medically intractable epilepsy.
This study analyzes the value of magnetic resonance imaging of the brain for patients with cancers that frequently metastasize to the brain.
This review describes the treatment options for neonatal brachial plexus palsy.
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