Explore the latest in nevi, including recent advances in imaging and in understanding risk for transformation to melanoma.
A girl in her teens presented with punctate keratotic papules on the palm and third finger, which had been present since the age of 2 years. What is your diagnosis?
This phase 2, open-label, placebo-controlled examines topical itraconazole as a treatment for basal cell carcinoma.
This case report describes a somatic p.Phe29del mutation of the connexin 26 gene (GJB2) manifesting as acantholytic dyskeratotic epidermal nevus.
This multicenter cohort study examines the outcomes and risk for the development of subsequent cutaneous melanoma in moderately dysplastic nevi excisionally biopsied without residual clinical pigmentation but with positive histologic margins, observed for 3 years or more.
This database study evaluated the efficacy of monitoring flat symmetric pigmented spitzoid-looking lesions in prepubertal children.
This longitudinal cohort study describes nevus acquisition from the ages of 3 to 16 years among white youths and evaluates variation by sex, Hispanic ethnicity, and body sites that are chronically vs intermittently exposed to the sun.
This study of 87 pathologists compares the use of digital whole-slide imaging vs traditional microscopy in pathologists’ ability to accurately interpret melanocytic lesions and reproduce correct diagnoses.
This report of cases describes the use of picosecond laser to treat acquired bilateral nevus of Ota–like macules.
A woman in her 20s presented with linear hyperkeratotic papules on her right arm in a Blaschkoid pattern. What is your diagnosis?
This large-scale analysis of pathology reports in electronic medical records, using the natural language processing technique, evaluates population-based distributions and pathologic characteristics of melanocytic proliferations.
This cohort study from the Study of Nevi in Children examines host, behavioral, and dermoscopic factors in early adolescence that are associated with a mole-prone phenotype in late adolescence.
A 4-year-old boy had a 1-cm well-circumscribed, symmetrical, pinkish, dome-shaped nodule with central erosions on the left cheek. Hair, nails, and mucosae were of normal appearance, and the remainder of the examination was unremarkable. What would you do next?
This case report describes induction of immune reaction to benign melanocytic nevi without halo during nivolumab therapy in a patient with melanoma.
This analysis of patient medical records and skin photography describes the clinical characteristics of connective tissue nevi on the trunk and extremities of patients with tuberous sclerosis complex.
This case report describes a patient with pembrolizumab-induced extensive panniculitis and nevus regression.
This case report describes a BRAF V600E mutation in involuting nevus in a patient treated with vemurafenib.
This study examines tattoo artists’ awareness of skin cancer and whether this influences the decision to refer clients with a suspicious lesion to a dermatologist.
This experimental study assesses the agreement of dermatologists on identification of the ugly duckling sign and estimates the contribution of intrapatient comparative analysis to the diagnosis of melanoma.
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