[Skip to Navigation]
Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue
JAMA Network Home
JAMA Network
HomeJN Learning / CMESubscribeJobs

Publications

JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959)

Multimedia

Podcasts Video
JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions
Terms of Use | Privacy Policy | Accessibility Statement
2023 American Medical Association. All Rights Reserved
    Sign In
    Individual Sign In
    Sign inCreate an Account
    Access through your institution
    Sign In
    Purchase Options:
    Subscriptions and More

    Targeted and Immune Cancer Therapy

    Explore the latest in targeted and immune therapies, including recent advances in precision therapies and in use of tumor checkpoint inhibitors.

    Add to My Interests
     
    Publication
    All Publications
    Apply
    Publication
    Article Type
    All Article Types
    Apply
    Article Type
    • Clinical Activity of Olvimulogene Nanivacirepvec–Primed Immunochemotherapy in Heavily Pretreated Patients With Platinum-Resistant or Platinum-Refractory Ovarian Cancer: The Nonrandomized Phase 2 VIRO-15 Clinical Trial
      JAMA Oncology
      Research
      May 25, 2023

      This nonrandomized phase 2 clinical trial examines the clinical activity of Olvi-Vec oncolytic immunotherapy and subsequent platinum-doublet chemotherapy with or without bevacizumab in women with platinum-resistant or -refractory ovarian cancers.

      Ovarian Cancer Gynecologic Cancer Gynecology Women's Health Obstetrics and Gynecology
      Full Text | pdf link PDF has multimedia
    • Comparison of Anti–Programmed Cell Death Ligand 1 Therapy Combinations vs Sunitinib for Metastatic Renal Cell Carcinoma: A Meta-analysis
      JAMA Network Open
      Research
      May 18, 2023

      This meta-analysis of 3 randomized clinical trials evaluates the association of combined anti–PD-L1 agents with survival and response rate among patients with metastatic renal cell carcinoma.

      Oncology Cancer Biomarkers Nephrology Urology Urologic Cancer
      Full Text | pdf link PDF open access
    • Panitumumab Plus Trifluridine-Tipiracil as Anti–Epidermal Growth Factor Receptor Rechallenge Therapy for Refractory RAS Wild-Type Metastatic Colorectal Cancer: A Phase 2 Randomized Clinical Trial
      JAMA Oncology
      Research
      May 18, 2023

      This randomized clinical trial assesses progression-free survival among patients with RAS wild-type metastatic colorectal cancer receiving panitumumab plus standard-of-care trifluridine-tipiracil as third-line therapy.

      Oncology Surgery Surgical Oncology Gastroenterology and Hepatology Colorectal Cancer
      Full Text | pdf link PDF open access
    • Assessment of Tyrosine Kinase Inhibitors and Survival and Cardiovascular Outcomes of Patients With Non–Small Cell Lung Cancer in Taiwan
      JAMA Network Open
      Research
      May 17, 2023

      This cohort study compares risk of death and major adverse cardiac and cerebrovascular events among patients with non–small cell lung cancer (NSCLC) receiving tyrosine kinase inhibitors (TKIs) vs those not receiving TKIs in a nationwide cohort in Taiwan.

      Oncology Adverse Drug Events Cardiovascular Risk Factors Cardiology Clinical Pharmacy and Pharmacology
      Full Text | pdf link PDF open access
    • Survival Outcomes in Patients With Hormone Receptor–Positive Metastatic Breast Cancer With Low or No ERBB2 Expression Treated With Targeted Therapies Plus Endocrine Therapy
      JAMA Network Open
      Research
      May 11, 2023

      This cohort study of women with hormone receptor–positive metastatic breast cancer treated with targeted therapy in combination with endocrine therapy compares the outcomes for those with low vs no ERBB2 expression.

      Oncology Cancer Genetics Cancer Biomarkers Genetics and Genomics Women's Health
      Full Text | pdf link PDF open access
    • Treatment of Netherton Syndrome With Abrocitinib
      JAMA Dermatology
      Case Report
      May 10, 2023

      This case report describes a 28-year-old woman with Netherton syndrome who had large erythematous migratory patches with serpiginous double-edged scales on her face, neck, trunk, and extremities.

      Dermatology
      Full Text | pdf link PDF
    • Red Flag on Electrocardiogram Findings in a Patient With Lung Cancer
      JAMA Internal Medicine
      Case Report
      May 8, 2023

      This case report describes a patient in their early 70s with sudden onset squeezing precordial chest pain, back pain, and nausea, and a history of long-term lung cancer treatment.

      Clinical Pharmacy and Pharmacology Emergency Medicine Lung Cancer Oncology Challenges in Clinical Electrocardiography
      Full Text | pdf link PDF | CME & MOC is active quiz
    • Assessment of Tumor Mutational Burden and Outcomes in Patients With Diverse Advanced Cancers Treated With Immunotherapy
      JAMA Network Open
      Research
      May 2, 2023

      This cohort study evaluates tumor mutational burden and outcomes in patients with diverse advanced cancers treated with immunotherapy.

      Oncology Cancer Biomarkers Genetics and Genomics Cancer Genetics
      Full Text | pdf link PDF open access
    • Clinical Trials Portfolio and Regulatory History of Idelalisib in Indolent Non-Hodgkin Lymphoma: A Systematic Review and Meta-analysis
      JAMA Internal Medicine
      Research
      May 1, 2023

      This systematic review with meta-analysis examines the regulatory oversight of the accelerated approval pathway and evidence generation for idelalisib during premarketing, postmarketing, and premarketing withdrawal periods.

      Hematology Oncology Health Care Safety Hematologic Cancer Lymphomas
      Full Text | pdf link PDF open access
    • Efficacy and Safety of Upadacitinib Treatment in Adolescents With Moderate-to-Severe Atopic Dermatitis: Analysis of the Measure Up 1, Measure Up 2, and AD Up Randomized Clinical Trials
      JAMA Dermatology
      Research
      May 1, 2023

      This analysis of 3 randomized clinical trials assesses the efficacy and safety of upadacitinib to treat moderate-to-severe atopic dermatitis in adolescents.

      Adolescent Medicine Pediatrics Atopic Dermatitis Dermatology Oncology
      Full Text | pdf link PDF open access
    • Pembrolizumab Added to Ifosfamide, Carboplatin, and Etoposide Chemotherapy for Relapsed or Refractory Classic Hodgkin Lymphoma: A Multi-institutional Phase 2 Investigator-Initiated Nonrandomized Clinical Trial
      JAMA Oncology
      Research
      May 1, 2023

      This nonrandomized clinical trial investigates the addition of pembrolizumab to ifosfamide, carboplatin, and etoposide chemotherapy and evaluates the response rate of patients with relapsed or refractory Hodgkin lymphoma.

      Oncology Hematologic Cancer Lymphomas Hematology
      Full Text | pdf link PDF
    • Regorafenib, Ipilimumab, and Nivolumab for Patients With Microsatellite Stable Colorectal Cancer and Disease Progression With Prior Chemotherapy: A Phase 1 Nonrandomized Clinical Trial
      JAMA Oncology
      Research
      May 1, 2023

      This nonrandomized clinical trial assesses the recommended phase 2 dose of regorafenib, ipilimumab, and nivolumab immunotherapy for patients with refractory microsatellite stable metastatic colorectal cancer.

      Colorectal Cancer Gastroenterology Gastrointestinal Cancer Oncology Gastroenterology and Hepatology
      Full Text | pdf link PDF
    • Immunotherapy Success for Microsatellite Stable Colorectal Cancers—Searching for the Horizon
      JAMA Oncology
      Opinion
      May 1, 2023
      Colorectal Cancer Gastroenterology Gastrointestinal Cancer Oncology Gastroenterology and Hepatology
      Full Text | pdf link PDF
    • Association of a Mediterranean Diet With Outcomes for Patients Treated With Immune Checkpoint Blockade for Advanced Melanoma
      JAMA Oncology
      Research
      May 1, 2023

      This cohort study examines the association between habitual diet and response to treatment with immune checkpoint blockade among patients with advanced melanoma.

      Lifestyle Behaviors Diet Dermatology Melanoma Oncology
      Full Text | pdf link PDF open access has multimedia
    • Practice-Level Variation in Molecular Testing and Use of Targeted Therapy for Patients With Non–Small Cell Lung Cancer and Colorectal Cancer
      JAMA Network Open
      Research
      April 28, 2023

      This cross-sectional study compares rates of molecular testing and targeted therapy among patients with non–small cell lung cancer (NSCLC) and colorectal cancer (CRC) use by practice type and across practices.

      Health Policy Pharmacy and Clinical Pharmacology Genetics and Genomics Lung Cancer Oncology
      Full Text | pdf link PDF open access
    • Response of Severe Lupus Miliaris Disseminatus Faciei to Treatment With Ruxolitinib Cream
      JAMA Dermatology
      Case Report
      April 26, 2023

      This case report describes a 46-year-old woman presented with numerous monomorphic, mildly erythematous, and skin-colored smooth indurated papules that coalesced into plaques that involved the upper and lower eyelids, forehead, medial cheeks, cutaneous lips, and chin.

      Dermatology Cosmetic Medicine, Non-Surgical Connective Tissue Disease of the Skin
      Full Text | pdf link PDF
    • Pembrolizumab Immunotherapy Improved Endometrial Cancer Survival
      JAMA
      News
      April 25, 2023
      Endometrial Cancer Oncology Gynecologic Cancer Gynecology Women's Health
      Full Text | pdf link PDF free
    • Advances in Ovarian Cancer Care and Unmet Treatment Needs for Patients With Platinum Resistance: A Narrative Review
      JAMA Oncology
      Review
      April 20, 2023

      This review summarizes the current and evolving treatment landscape for platinum-resistant ovarian cancer and highlights the development of promising novel compounds.

      Oncology Ovarian Cancer Gynecologic Cancer Gynecology Women's Health
      Full Text | pdf link PDF | CME & MOC is active quiz
    • Revumenib Appears Safe in Leukemia Trial, Yields Remission in Some
      JAMA
      News
      April 18, 2023
      Hematology Oncology Hematologic Cancer Leukemias
      Full Text | pdf link PDF free
    • Panitumumab vs Bevacizumab Added to Standard First-line Chemotherapy and Overall Survival Among Patients With RAS Wild-type, Left-Sided Metastatic Colorectal Cancer: A Randomized Clinical Trial
      JAMA
      Research
      April 18, 2023

      This randomized clinical trial assesses the effect of adding panitumumab vs bevacizumab to standard first-line chemotherapy on overall survival among patients with RAS wild-type, left-sided, metastatic colorectal cancer.

      Oncology Gastroenterology and Hepatology Colorectal Cancer Gastroenterology Gastrointestinal Cancer
      Full Text | pdf link PDF
    1 2 3 4 5 … 64
    Next 20 Results »
    Get the latest from JAMA Network
    Sign Up
    Privacy Policy | Terms of Use
     

    Select Your Interests

    Customize your JAMA Network experience by selecting one or more topics from the list below.

    • Academic Medicine
    • Acid Base, Electrolytes, Fluids
    • Allergy and Clinical Immunology
    • Anesthesiology
    • Anticoagulation
    • Art and Images in Psychiatry
    • Assisted Reproduction
    • Bleeding and Transfusion
    • Cardiology
    • Caring for the Critically Ill Patient
    • Challenges in Clinical Electrocardiography
    • Climate and Health
    • Clinical Challenge
    • Clinical Decision Support
    • Clinical Implications of Basic Neuroscience
    • Clinical Pharmacy and Pharmacology
    • Complementary and Alternative Medicine
    • Consensus Statements
    • Coronavirus (COVID-19)
    • Critical Care Medicine
    • Cultural Competency
    • Dental Medicine
    • Dermatology
    • Diabetes and Endocrinology
    • Diagnostic Test Interpretation
    • Drug Development
    • Electronic Health Records
    • Emergency Medicine
    • End of Life
    • Environmental Health
    • Equity, Diversity, and Inclusion
    • Ethics
    • Facial Plastic Surgery
    • Gastroenterology and Hepatology
    • Genetics and Genomics
    • Genomics and Precision Health
    • Geriatrics
    • Global Health
    • Guide to Statistics and Methods
    • Guidelines
    • Hair Disorders
    • Health Care Delivery Models
    • Health Care Economics, Insurance, Payment
    • Health Care Quality
    • Health Care Reform
    • Health Care Safety
    • Health Care Workforce
    • Health Disparities
    • Health Inequities
    • Health Informatics
    • Health Policy
    • Hematology
    • History of Medicine
    • Humanities
    • Hypertension
    • Images in Neurology
    • Implementation Science
    • Infectious Diseases
    • Innovations in Health Care Delivery
    • JAMA Infographic
    • Law and Medicine
    • Leading Change
    • Less is More
    • LGBTQIA Medicine
    • Lifestyle Behaviors
    • Medical Coding
    • Medical Devices and Equipment
    • Medical Education
    • Medical Education and Training
    • Medical Journals and Publishing
    • Melanoma
    • Mobile Health and Telemedicine
    • Narrative Medicine
    • Nephrology
    • Neurology
    • Neuroscience and Psychiatry
    • Notable Notes
    • Nursing
    • Nutrition
    • Nutrition, Obesity, Exercise
    • Obesity
    • Obstetrics and Gynecology
    • Occupational Health
    • Oncology
    • Ophthalmology
    • Orthopedics
    • Otolaryngology
    • Pain Medicine
    • Pathology and Laboratory Medicine
    • Patient Care
    • Patient Information
    • Pediatrics
    • Performance Improvement
    • Performance Measures
    • Perioperative Care and Consultation
    • Pharmacoeconomics
    • Pharmacoepidemiology
    • Pharmacogenetics
    • Pharmacy and Clinical Pharmacology
    • Physical Medicine and Rehabilitation
    • Physical Therapy
    • Physician Leadership
    • Poetry
    • Population Health
    • Professional Well-being
    • Professionalism
    • Psychiatry and Behavioral Health
    • Public Health
    • Pulmonary Medicine
    • Radiology
    • Regulatory Agencies
    • Research, Methods, Statistics
    • Resuscitation
    • Rheumatology
    • Risk Management
    • Scientific Discovery and the Future of Medicine
    • Shared Decision Making and Communication
    • Sleep Medicine
    • Sports Medicine
    • Stem Cell Transplantation
    • Substance Use and Addiction Medicine
    • Surgery
    • Surgical Innovation
    • Surgical Pearls
    • Teachable Moment
    • Technology and Finance
    • The Art of JAMA
    • The Arts and Medicine
    • The Rational Clinical Examination
    • Tobacco and e-Cigarettes
    • Toxicology
    • Translational Medicine
    • Trauma and Injury
    • Treatment Adherence
    • Ultrasonography
    • Urology
    • Users' Guide to the Medical Literature
    • Vaccination
    • Venous Thromboembolism
    • Veterans Health
    • Violence
    • Women's Health
    • Workflow and Process
    • Wound Care, Infection, Healing
    Save Preferences
    Privacy Policy | Terms of Use
    X

    JAMA Network

    Content

    Home Podcasts Video Featured Content
    JN Learning / CME Store Jobs Institutions Reprints & Permissions

    Subscribe

    Go

    JAMA Network

    Publications

    JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959)

    Sites

    Art and Images in Psychiatry Best of the JAMA Network Clinical Crosswords from JAMA Coronavirus Resource Center Evidence-Based Medicine: An Oral History Fishbein Fellowship Genomics and Precision Health Hypertension JAMA Forum Archive JAMA Network Audio JAMA Network Video JAMA Network Conferences JAMA Surgery Guide to Statistics and Methods Machine Learning Medical News Mpox (Monkeypox) Research Ethics Topics and Collections Visual Abstracts War and Health

    Featured Articles

    Antiretroviral Drugs for HIV Treatment and Prevention in Adults - 2022 IAS-USA Recommendations CONSERVE 2021 Guidelines for Reporting Trials Modified for the COVID-19 Pandemic Global Burden of Cancer, 2010-2019 Global Burden of Long COVID Global Burden of Skin Diseases, 1990-2017 Guidelines for Reporting Outcomes in Trial Protocols: The SPIRIT-Outcomes 2022 Extension Mass Violence and the Complex Spectrum of Mental Illness and Mental Functioning Organization and Performance of US Health Systems Spirituality in Serious Illness and Health The US Medicaid Program: Coverage, Financing, Reforms, and Implications for Health Equity

    USPSTF Recommendation Statements

    Screening for Colorectal Cancer Screening for Hypertension Screening for Lung Cancer Screening for Prediabetes and Type 2 Diabetes Statins for Primary Prevention of Cardiovascular Disease Vitamin and Mineral Supplements for Primary Prevention of of Cardiovascular Disease and Cancer

    Blogs

    AMA Style Insider

    Information

    For Authors For Institutions & Librarians For Advertisers For Subscription Agents For Employers & Job Seekers For the Media Equity, Diversity, Inclusion Online Commenting Policy Public Access and Open Access Policy Statement on Potentially Offensive Content

    JAMA Network Products

    AMA Manual of Style JAMAevidence Peer Review Congress

    JN Learning

    Home State CME Clinical Challenge CME Atrial Fibrillation Course Women's Health Course CME / MOC Reporting Preferences About CME & MOC

    Help

    Subscriptions & Renewals Manage Emails Update My Address Contact Us My Account

    JAMA Career Center

    Physician Job Listings
     
    Get the latest from JAMA Network
    Sign Up
    Privacy Policy | Terms of Use
    Jama Network Logo

    © 2023 American Medical Association. All Rights Reserved.
    Terms of Use| Privacy Policy| Accessibility Statement

    Silverchair Logo
    .
    ×
    Access your subscriptions

    Add or change institution
    Free access to newly published articles

    To register for email alerts with links to free full-text articles
    Purchase access

    Get full journal access for 1 year
    Get unlimited access and a printable PDF ($40.00)—
    Sign in or create a free account
    Access your subscriptions

    Add or change institution
    Free access to newly published articles

    To register for email alerts with links to free full-text articles
    Purchase access

    Get full journal access for 1 year
    Get unlimited access and a printable PDF ($40.00)—
    Sign in or create a free account
    Sign in to access free PDF

    Add or change institution
    Free access to newly published articles

    To register for email alerts with links to free full-text articles
    Save your search

    Free access to newly published articles

    To register for email alerts with links to free full-text articles
    Purchase access

    Customize your interests

    Free access to newly published articles

    To register for email alerts with links to free full-text articles
    Create a personal account or sign in to:
    • Register for email alerts with links to free full-text articles
    • Access PDFs of free articles
    • Manage your interests
    • Save searches and receive search alerts
    Privacy Policy
    Make a comment

    Free access to newly published articles

    To register for email alerts with links to free full-text articles
    Create a personal account or sign in to:
    • Register for email alerts with links to free full-text articles
    • Access PDFs of free articles
    • Manage your interests
    • Save searches and receive search alerts
    Privacy Policy