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    Oncology

    Explore the latest in oncology, including recent guidelines and advances in the screening, diagnosis, and treatment of breast and lung cancer.

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    • Prevaccination Prevalence of Type-Specific Human Papillomavirus Infection by Grade of Cervical Cytology in Estonia
      JAMA Network Open
      Research
      February 6, 2023

      This cross-sectional study examines the prevaccination prevalence of high-risk human papillomavirus (HPV) and type distribution by cervical cytology grade in Estonia.

      Infectious Diseases Global Health Cervical Cancer Gynecologic Cancer Gynecology
      Full Text | pdf link PDF open access
    • Association of Anthracycline With Heart Failure in Patients Treated for Breast Cancer or Lymphoma, 1985-2010
      JAMA Network Open
      Research
      February 3, 2023

      This case-control study compares the long-term incidence of congestive heart failure in patients treated for breast cancer or lymphoma with anthracycline therapy compared with healthy controls from the same community.

      Cardiology Breast Cancer Women's Health Heart Failure Hematology
      Full Text | pdf link PDF open access
    • Assessment of Cancer Predisposition Syndromes in a National Cohort of Children With a Neoplasm
      JAMA Network Open
      Research
      February 3, 2023

      This cohort study examines a Dutch national children’s cancer center’s experience in diagnosing cancer predisposition syndromes before introducing routine next-generation genetic sequencing.

      Pediatrics Cancer Genetics Pediatric Cancer Genetics and Genomics
      Full Text | pdf link PDF open access
    • Opening the Windows for More Effective and Equitable Cancer Screening
      JAMA Network Open
      Opinion
      February 3, 2023
      Public Health Radiology Women's Health Coronavirus (COVID-19) Breast Cancer
      Full Text | pdf link PDF open access
    • Heart Failure in Patients With Cancer Treated With Anthracyclines—Revisiting the Foundation of Cardio-Oncology
      JAMA Network Open
      Opinion
      February 3, 2023
      Cardiology Breast Cancer Hematology Hematologic Cancer Lymphomas
      Full Text | pdf link PDF open access
    • Breast and Lung Cancer Screening Among Medicare Enrollees During the COVID-19 Pandemic
      JAMA Network Open
      Research
      February 3, 2023

      This cohort study examines the observed vs expected mammography and low-dose computed tomographic scan rates from the beginning of the COVID-19 pandemic through April 2022.

      Public Health Radiology Women's Health Breast Cancer Cancer Screening, Prevention, Control
      Full Text | pdf link PDF open access
    • Clinical Importance of Clonal Hematopoiesis in Metastatic Gastrointestinal Tract Cancers
      JAMA Network Open
      Research
      February 2, 2023

      This cohort study assesses the association of clonal hematopoiesis with progression-free and overall survival among patients with metastatic colorectal and esophagogastric cancers who were undergoing treatment with first-line chemotherapy or immunotherapy.

      Genetics and Genomics Hematology Cancer Genetics
      Full Text | pdf link PDF open access
    • Lip Squamous Cell Carcinoma With Spontaneous Eruption and Drainage
      JAMA Otolaryngology–Head & Neck Surgery
      Case Report
      February 2, 2023

      A 69-year-old woman with a newly diagnosed squamous cell carcinoma of the lower lip mucosa presented 3 days after initiating neoadjuvant immune checkpoint blockade immunotherapy with redness and swelling of the tumor site. What is your diagnosis?

      Dermatology Targeted and Immune Cancer Therapy Surgery Surgical Oncology Clinical Challenge
      Full Text | pdf link PDF | CME & MOC is active quiz
    • Different Ways of Traveling the Cancer Road—Daytime Running Lights at Night?
      JAMA Oncology
      Opinion
      February 2, 2023

      This essay describes the reflections of an oncology ward attending physician and patients with cancer who are blindsided by cancer recurrence or progression.

      Humanities Narrative Medicine Cancer Care Chronicles
      Full Text | pdf link PDF
    • Association of Radiation and Procarbazine Dose With Risk of Colorectal Cancer Among Survivors of Hodgkin Lymphoma
      JAMA Oncology
      Research
      February 2, 2023

      This nested case-control study of 5-year Hodgkin lymphoma survivors explores dose-response associations of radiation therapy and procarbazine with colorectal cancer.

      Colorectal Cancer Gastroenterology Gastrointestinal Cancer Cancer Survivorship Gastroenterology and Hepatology
      Full Text | pdf link PDF open access
    • Breast Cancer Diagnosis, Treatment, and Outcomes of Patients From Sex and Gender Minority Groups
      JAMA Oncology
      Research
      February 2, 2023

      This case-control study investigates the quality of breast cancer treatment and recurrence outcomes for patients from sex and gender minority groups compared with cisgender heterosexual patients.

      Breast Cancer Health Disparities Women's Health LGBTQIA Medicine
      Full Text | pdf link PDF
    • Increased Tumor Mutation Burden Levels and Sensitivity of Non–Small Cell Lung Cancer to PD-L1 Blockade—Reply
      JAMA Oncology
      Letter
      February 2, 2023
      Full Text | pdf link PDF
    • Increased Tumor Mutation Burden Levels and Sensitivity of Non–Small Cell Lung Cancer to PD-L1 Blockade
      JAMA Oncology
      Letter
      February 2, 2023
      Full Text | pdf link PDF
    • Increased Tumor Mutation Burden Levels and Sensitivity of Non–Small Cell Lung Cancer to PD-L1 Blockade
      JAMA Oncology
      Letter
      February 2, 2023
      Full Text | pdf link PDF
    • Cardiovascular Magnetic Resonance Imaging in Patients With Ibrutinib-Associated Cardiotoxicity
      JAMA Oncology
      Research
      February 2, 2023

      This cohort study of consecutive patients imaged with cardiac magnetic resonance imaging examines the prevelance of ibrutinib-associated cardiotoxic effects.

      Clinical Pharmacy and Pharmacology Adverse Drug Events Radiology Cardiac Imaging Targeted and Immune Cancer Therapy
      Full Text | pdf link PDF
    • Factor Analysis of Health Care Access With Ovarian Cancer Surgery and Gynecologic Oncologist Consultation
      JAMA Network Open
      Research
      February 1, 2023

      This cohort study assesses health care affordability, availability, and accessibility along with race and ethnicity in association with receipt of guideline-adherent care for ovarian cancer.

      Ovarian Cancer Surgery Surgical Oncology Gynecology Women's Health
      Full Text | pdf link PDF open access
    • Frequency and Characteristics of Trials Using Medical Writer Support in High-Impact Oncology Journals
      JAMA Network Open
      Research
      February 1, 2023

      This cross-sectional study reviews original oncology trials to assess whether the declared use of medical writers is associated with trial success and the use of a particular type of end point.

      Medical Journals and Publishing
      Full Text | pdf link PDF open access
    • Effect of Focal vs Extended Irreversible Electroporation for the Ablation of Localized Low- or Intermediate-Risk Prostate Cancer on Early Oncological Control: A Randomized Clinical Trial
      JAMA Surgery
      Research
      February 1, 2023

      This randomized clinical trial compares data for patients who underwent ablation therapy to determine the effects of focal vs extended irreversible electroporation on early oncological control as indicated by presence on follow-up biopsy of clinically significant prostate cancer.

      Surgery Surgical Oncology Pathology and Laboratory Medicine Prostate Cancer Urology
      Full Text | pdf link PDF
    • Prostate Cancer Recurrence and Persistence After Irreversible Electroporation Focal Ablation
      JAMA Surgery
      Opinion
      February 1, 2023
      Prostate Cancer Surgery Surgical Oncology Urology Urologic Cancer
      Full Text | pdf link PDF
    • Agent Slows Glioblastoma Tumors in Mice by Blocking Fat Metabolism
      JAMA
      News
      February 1, 2023
      Neuro-oncology Neurology Targeted and Immune Cancer Therapy
      Full Text | pdf link PDF free
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