Explore the latest in oncology, including recent guidelines and advances in the screening, diagnosis, and treatment of breast and lung cancer.
This Viewpoint discusses the practice of using a clock timer analogy to describe population risks of cancer and suggests standardizing the measures of incidence rates used in the clocks to population size to facilitate more accurate comparisons between populations.
This survey study assesses patient attitudes and preferences about cessation of low-value colorectal cancer screening and their overall comfort using age, life expectancy calculators, and colorectal cancer risk calculators in helping make individualized screening decisions.
This case-control cohort study compares the total number of opioid pain medications prescribed after gynecologic and abdominal surgery, the number of requests for opioid prescription refills, and postoperative pain scores and complications before and after implementation of an ultrarestrictive opioid prescription protocol.
This systematic review and meta-analysis examines randomized clinical trials (RCTs) of modern cancer drugs in the adjuvant setting to determine the incidence of severe adverse events reported in placebo groups.
This cohort study compares proportions of women in provincial prison vs women in the general population who were up-to-date for cervical cancer screening between 2006 and 2013 in Ontario, Canada.
This Viewpoint reviews the benefits and risks of risk-reducing mastectomy in otherwise healthy women with BRCA1 and BRCA2 mutations to inform discussions about the proceeding with or foregoing the procedure, and it calls for continued research to understand how to better individualize risk and prevent disease nonsurgically.
This study matches entries in ClinicalTrials.gov for cancer drug trials at initiation of the trial with later entries and with journal reports of the trials to assess modifications in trial design, external factors associated with such modifications, and transparency in reporting them.
This secondary analysis of a randomized clinical trial examines the association of modern chemoradiotherapy with survival among patients with stage I to II small cell lung cancer compared with that among patients with stage III small cell lung cancer.
This study examines HER2 ISH-equivocal breast cancers to asses 2013/2014 American Society of Clinical Oncology and College of American Pathologists guidelines in determining HER2-positive or HER2-negative breast cancers and false-positive results.
This secondary analysis of the Women’s Health Initiative randomized clinical trial and observational study cohort investigates the association between body fat and breast cancer risk in postmenopausal women with normal body mass index.
This case series describes the clinicopathologic features of and identifies factors associated with aggressive squamous cell carcinoma in solid organ transplant recipients.
This Medical News article discusses the top-viewed articles published in the JAMA family of journals over the past year.
This JAMA Clinical Guidelines Synopsis summarizes the 2017 Fleischner Society guidelines on management of incidental pulmonary nodules detected on computed tomography (CT) imaging.
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