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    Otolaryngology

    Explore the latest in otolaryngology, including diagnosis and management of common sinus and vestibular disorders and head and neck cancers.

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    • Margin Assessment Methods in Oral Cavity Squamous Cell Carcinoma and Recurrence: Tumor Bed vs Resection Specimen Sampling
      JAMA Otolaryngology–Head & Neck Surgery
      Research
      September 28, 2023

      This retrospective study of margin assessment methods after oral cavity squamous cell carcinoma resection compares tumor bed vs resection specimen sampling and the risk of recurrence.

      Surgical Oncology Dental Medicine Head and Neck Cancer Oncology Perioperative Care and Consultation
      Full Text | pdf link PDF
    • Selective Deep Lobe Parotidectomy vs Total Parotidectomy for Patients With Benign Deep Lobe Parotid Tumors
      JAMA Otolaryngology–Head & Neck Surgery
      Research
      September 28, 2023

      This case series compares selective deep lobe parotidectomy vs total parotidectomy for patients with benign tumors in the deep lobe for postoperative complications and tumor control and recurrence.

      Head and Neck Cancer Salivary Gland Disorders Head and Neck Surgery Facial Nerve
      Full Text | pdf link PDF
    • Virtual Tumor Board to Foster Interinstitutional Head and Neck Cancer Subspecialty Care
      JAMA Otolaryngology–Head & Neck Surgery
      Research
      September 28, 2023

      This cross-sectional study evaluates the concordance on treatment and diagnostic recommendations between clinicians at 2 collaborating health systems.

      Head and Neck Cancer Oncology
      Full Text | pdf link PDF
    • Radiotherapy Plus Cisplatin With or Without Lapatinib for Non–Human Papillomavirus Head and Neck Carcinoma: A Phase 2 Randomized Clinical Trial
      JAMA Oncology
      Research
      September 28, 2023

      This randomized clinical trial examines whether lapatinib combined with a cisplatin-based combination radiation regimen is effective for the treatment of patients with locally advanced head and neck cancer with poor prognosis.

      Targeted and Immune Cancer Therapy Oncology Cancer Biomarkers Head and Neck Cancer Radiation Oncology
      Full Text | pdf link PDF
    • Most People With GERD Don’t Have Increased Esophageal Cancer Risk
      JAMA
      News
      September 27, 2023
      Esophageal Disease Gastroenterology Cancer Epidemiology Gastroenterology and Hepatology Gastroesophageal Reflux
      Full Text | pdf link PDF free
    • Head and Neck Surgery—The Call to Joyful Sacrificial Giving
      JAMA Otolaryngology–Head & Neck Surgery
      Opinion
      September 21, 2023

      This Viewpoint explores the role of the servant leader and its implications as a leadership model for head and neck surgeons.

      Head and Neck Surgery Surgery
      Full Text | pdf link PDF
    • A Congenital Tongue Mass
      JAMA Otolaryngology–Head & Neck Surgery
      Case Report
      September 21, 2023

      A 13-month-old male presents with a firm left anterior tongue mass noted since birth that has increased proportionally with the child’s growth. What is your diagnosis?

      Pediatrics Clinical Challenge
      Full Text | pdf link PDF | CME & MOC is active quiz
    • Efficacy of Gabapentin For Post–COVID-19 Olfactory Dysfunction: The GRACE Randomized Clinical Trial
      JAMA Otolaryngology–Head & Neck Surgery
      Research
      September 21, 2023

      This randomized clinical trial examines the safety and efficacy of gabapentin for patients with COVID-19–induced olfactory dysfunction.

      Coronavirus (COVID-19) Olfaction and Taste
      Full Text | pdf link PDF free has multimedia
    • Treatment Failure and Adverse Events After Amoxicillin-Clavulanate vs Amoxicillin for Pediatric Acute Sinusitis
      JAMA
      Research
      September 19, 2023

      This cohort study compares the rate of treatment failure and adverse events associated with amoxicillin-clavulanate vs amoxicillin in children newly diagnosed with acute sinusitis in an outpatient setting.

      Emergency Medicine Infectious Diseases Antibiotic Use, Overuse, Resistance, Stewardship Rhinology Pediatrics
      Full Text | pdf link PDF
    • One in 5 Males Worldwide Has High-Risk Genital HPV
      JAMA
      News
      September 19, 2023
      Adolescent Medicine Cervical Cancer Head and Neck Cancer Infectious Diseases Pediatrics
      Full Text | pdf link PDF
    • Hearing Impairment and School Engagement Outcomes in US Children
      JAMA Otolaryngology–Head & Neck Surgery
      Research
      September 14, 2023

      This cross-sectional study uses data from the 2016-2021 National Survey of Children’s Health to examine the associations between hearing loss, its sequelae, and school engagement measures among school-aged children in the US.

      Audiology and Hearing Pediatrics Child and Adolescent Psychiatry
      Full Text | pdf link PDF
    • Use of Physical Therapy and Subsequent Falls Among Patients With Dizziness in the US
      JAMA Otolaryngology–Head & Neck Surgery
      Research
      September 14, 2023

      This cohort study examines the association between the receipt of physical therapy to treat dizziness and the risk of falls requiring medical care in the subsequent year.

      Neurology Physical Therapy Audiology and Hearing Otology
      Full Text | pdf link PDF
    • Concordance of the ACR TI-RADS Classification With Bethesda Scoring and Histopathology Risk Stratification of Thyroid Nodules
      JAMA Network Open
      Research
      September 13, 2023

      This cohort study examines the concordance of American College of Radiology Thyroid Imaging Reporting and Data System (ACR-TIRADS) classification with Bethesda classification and histopathology for thyroid nodules.

      Pathology and Laboratory Medicine Endocrinology Thyroid Disorders Diabetes and Endocrinology Oncology
      Full Text | pdf link PDF open access
    • Efficacy and Tolerability of Gefapixant for Treatment of Refractory or Unexplained Chronic Cough: A Systematic Review and Dose-Response Meta-Analysis
      JAMA
      Research
      September 11, 2023

      This systematic review and dose-response meta-analysis evaluates the efficacy and tolerability of gefapixant, a new P2X3 antagonist, for the treatment of adults with refractory or unexplained chronic cough.

      Pulmonary Medicine
      Full Text | pdf link PDF
    • Gefapixant for Refractory or Unexplained Chronic Cough?
      JAMA
      Opinion
      September 11, 2023
      Pulmonary Medicine
      Full Text | pdf link PDF
    • The Global, Regional, and National Burden of Adult Lip, Oral, and Pharyngeal Cancer in 204 Countries and Territories: A Systematic Analysis for the Global Burden of Disease Study 2019
      JAMA Oncology
      Research
      September 7, 2023

      This systematic analysis assesses the total and risk-attributable burden of lip and oral cavity cancer and other pharyngeal cancer for 204 countries and territories and by Socio-demographic Index using 2019 Global Burden of Diseases, Injuries, and Risk Factors Study estimates.

      Global Health Head and Neck Cancer Oncology Dental Medicine Tobacco and e-Cigarettes
      Full Text | pdf link PDF open access
    • Elexacaftor-Tezacaftor-Ivacaftor Therapy for Chronic Sinus Disease in Cystic Fibrosis
      JAMA Otolaryngology–Head & Neck Surgery
      Research
      September 7, 2023

      This cohort study quantifies the 1-year outcomes of elexacaftor-tezacaftor-ivacaftor therapy for chronic rhinosinusitis based on changes in sinus computed tomography using the Lund-Mackay and Sheikh-Lind scoring systems among individuals with cystic fibrosis.

      Rhinology Pulmonary Medicine Adolescent Medicine Pediatrics
      Full Text | pdf link PDF
    • Opioid-Free Discharge After Pancreatic Resection Through a Learning Health System Paradigm
      JAMA Surgery
      Research
      September 6, 2023

      This cohort study analyzes the outcomes of iterative risk-stratified clinical pathways associated with inpatient and discharge opioid volumes after pancreatectomy.

      Pain Medicine Substance Use and Addiction Medicine Opioids Otology Pancreatic Surgery
      Full Text | pdf link PDF
    • Violaceous Plaque With Blackish Papules and Nodules in an Elderly Man
      JAMA Dermatology
      Case Report
      September 1, 2023

      A man in his 80s presents with a 3-month history of a violaceous plaque with blackish papules and nodules on his left cheek, neck, and chest. What is your diagnosis?

      Dermatology Oncology Salivary Gland Disorders Clinical Challenge Geriatrics
      Full Text | pdf link PDF | CME & MOC is active quiz
    • Single-Case Experimental Designs and N-of-1 Trials—An Alternative to Randomized Clinical Trials for Clinical Research in Otorhinolaryngology
      JAMA Otolaryngology–Head & Neck Surgery
      Opinion
      September 1, 2023

      This Viewpoint explores the use of single-case experimental designs in otolaryngology research.

      Research, Methods, Statistics
      Full Text | pdf link PDF
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