Explore the latest in radiation oncology from The JAMA Network, including recent advances in technologies and treatments and long-term radiotherapy complications.
This analysis examines the characteristics of radiotherapy interventional trials compared with other oncological interventional trials reported in ClinicalTrials.gov from 2007 through 2017.
This multi-institutional cohort study compares adjuvant radiotherapy with early-salvage radiotherapy used to manage postoperative patients with prostate cancer who have adverse pathological features.
This single-arm, phase 2 clinical trial evaluates the margin-negative resection rate in borderline-resectable pancreatic ductal adenocarcinoma after neoadjuvant FOLFIRINOX (fluorouracil, irinotecan, and oxaliplatin) therapy and individualized chemoradiotherapy.
This cohort study determines whether circulating tumor cell status is associated with radiotherapeutic benefit in terms of overall, local recurrence-free, and disease-free survival in patients with early-stage breast cancer.
This case report describes a patient with monolateral Favre-Racouchot syndrome following long-term exposure to infrared waves.
This randomized clinical trial evaluates the efficacy and safety of transarterial chemoembolization plus external beam radiotherapy compared with sorafenib in patients with hepatocellular carcinoma and macroscopic vascular invasion.
This propensity score matching cohort analysis compares the overall survival between adjuvant chemotherapy and postoperative observation in patients with rectal cancer with pathologic complete response following neoadjuvant chemoradiotherapy and resection.
This propensity score–matched cohort study examines whether adjuvant chemotherapy is associated with improved overall survival in patients with rectal cancer and pathological complete response following neoadjuvant chemoradiation therapy and resection.
This cohort study evaluates whether the HSD3B1 (1245C) allele is associated with worse clinical outcomes from androgen-deprivation therapy for biochemical recurrence after radiotherapy.
This randomized clinical trial investigates the benefit of concurrent chemoradiotherapy vs radiotherapy alone in patients with International Federation of Gynecology and Obstetrics (FIGO) stage IIIB squamous cell carcinoma of the uterine cervix.
Using data from the National Cancer Database, this cohort study examines the association of delayed time to radiotherapy with survival outcomes in patients with head and neck squamous cell carcinoma.
This Viewpoint examines the evidence supporting the efficacy of intraoperative radiation therapy compared with other treatment modalities for patients with early-stage breast cancer.
This study compares preoperative chemoradiation followed by postoperative adjuvant chemotherapy vs total neoadjuvant therapy for treatment of locally advanced rectal cancer.
This randomized clinical trial assesses whether dose-escalated radiation therapy vs standard dose improves survival for men with intermediate-risk prostate cancer.
This cohort study compares mortality and disease progression in patients with Gleason score 9-10 (aggressive) prostate cancer treated with external beam radiotherapy plus androgen deprivation therapy, radiotherapy plus brachytherapy boost, or radical prostatectomy.
This Viewpoint examines the generalizability of the results of ProtecT Trial to minority populations.
This population-based cohort study examines the association of radiotherapy for Hodgkin lymphoma with risk of ER-positive and ER-negative breast cancers using data from the US National Cancer Institute Surveillance, Epidemiology, and End Results database.
This cohort study examines the use of local excision among patients with T1 squamous cell carcinoma of the anal canal and compares the overall survival relative to those who received standard treatment with chemoradiotherapy.
This cohort study evaluates the clinical outcomes in patients with metastatic lung cancer treated with PD-1/PD-L1 inhibitors and thoracic radiotherapy.
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