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    Rheumatoid Arthritis

    Explore the latest in rheumatoid arthritis, including recent advances in treatment of RA and in prevention of its systemic complications.

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    • Monotreatment With Conventional Antirheumatic Drugs or Glucocorticoids in Rheumatoid Arthritis: A Network Meta-Analysis
      JAMA Network Open
      Research
      October 6, 2023

      The meta-analysis investigates the association of conventional antirheumatic drugs and glucocorticoids with clinical outcomes among patients with rheumatoid arthritis.

      Rheumatology Pharmacy and Clinical Pharmacology Clinical Pharmacy and Pharmacology
      Full Text | pdf link PDF open access
    • Aortic Stenosis Risk in Rheumatoid Arthritis
      JAMA Internal Medicine
      Research
      September 1, 2023

      This cohort study assesses the association between the risk of aortic stenosis and rheumatoid arthritis.

      Valvular Heart Disease Cardiology Rheumatology
      Full Text | pdf link PDF
    • Response to Biologic Drugs in Patients With Rheumatoid Arthritis and Antidrug Antibodies
      JAMA Network Open
      Research
      July 12, 2023

      This cohort study evaluates the association between the presence of antidrug antibodies and response to biologic disease–modifying antirheumatic drugs, including adalimumab, infliximab, etanercept, tocilizumab, and rituximab, in adults with rheumatoid arthritis (RA).

      Rheumatology Allergy and Clinical Immunology
      Full Text | pdf link PDF open access
    • Estimating Patient-Specific Relative Benefit of Adding Biologics to Conventional Rheumatoid Arthritis Treatment: An Individual Participant Data Meta-Analysis
      JAMA Network Open
      Research
      June 30, 2023

      This individual participant data meta-analysis estimates patient-specific outcomes of adding biologics to conventional synthetic disease-modifying antirheumatic drugs for the treatment of rheumatoid arthritis.

      Rheumatology
      Full Text | pdf link PDF open access
    • Comparative Effectiveness of Adalimumab vs Tofacitinib in Patients With Rheumatoid Arthritis in Australia
      JAMA Network Open
      Research
      June 29, 2023

      This comparative effectiveness reseach study assesses the effecetiveness of adalimumab vs tofacitinib for treatment of rheumatoid arthiritis in the clinical setting.

      Rheumatology Targeted and Immune Cancer Therapy Oncology
      Full Text | pdf link PDF open access
    • Rheumatoid Arthritis and Risk of Parkinson Disease in Korea
      JAMA Neurology
      Research
      June 1, 2023

      This cohort study evaluates the associations of rheumatoid arthritis and its seropositivity with subsequent Parkinson disease risk in a nationally representative Korean population.

      Movement Disorders Neurology Parkinson Disease Rheumatology
      Full Text | pdf link PDF
    • Therapeutic Equivalence of Biosimilar and Reference Biologic Drugs in Rheumatoid Arthritis: A Systematic Review and Meta-analysis
      JAMA Network Open
      Research
      May 26, 2023

      This systematic review and meta-analysis assesses the efficacy, safety, and immunogenicity associated with biosimilars of adalimumab, etanercept, and infliximab compared with their reference biologics for patients with rheumatoid arthritis.

      Rheumatology Pharmacy and Clinical Pharmacology Clinical Pharmacy and Pharmacology
      Full Text | pdf link PDF open access
    • Management of Rheumatoid Arthritis With a Digital Health Application: A Multicenter, Pragmatic Randomized Clinical Trial
      JAMA Network Open
      Research
      April 14, 2023

      This randomized clinical trial investigates whether using digital health applications to assess patient-reported outcomes could result in disease control in patients with rheumatoid arthritis at 22 tertiary hospitals in China.

      Rheumatology Health Informatics Mobile Health and Telemedicine Health Care Delivery Models
      Full Text | pdf link PDF open access
    • Discontinuation of Conventional Synthetic Disease-Modifying Antirheumatic Drugs in Patients With Rheumatoid Arthritis and Excellent Disease Control
      JAMA
      Research
      March 28, 2023

      This open-label randomized clinical trial assessed the 12-month risk of disease activity flares after discontinuation of conventional synthetic DMARDs (csDMARDs) compared with continuing half-dose csDMARDs in adult Norwegian patients with rheumatoid arthritis and excellent disease control.

      Rheumatology
      Full Text | pdf link PDF free
    • Incidence of Interstitial Lung Disease in Patients With Rheumatoid Arthritis Treated With Biologic and Targeted Synthetic Disease-Modifying Antirheumatic Drugs
      JAMA Network Open
      Research
      March 20, 2023

      This cohort study evaluates the incidence of interstitial lung disease in patients with rheumatoid arthritis who have been treated with biologic and targeted synthetic disease-modifying antirheumatic drugs.

      Rheumatology Pulmonary Medicine Oncology
      Full Text | pdf link PDF open access
    • Factors Associated With Quality Care Among Adults With Rheumatoid Arthritis
      JAMA Network Open
      Research
      December 12, 2022

      This cohort study assesses the prevalence of meeting successive markers of quality care for individuals with rheumatoid arthritis and characteristics associated with meeting these markers.

      Rheumatology Health Care Quality Gastroenterology and Hepatology Infectious Diseases Viral Hepatitis
      Full Text | pdf link PDF open access
    • Assessment of Risk of Rheumatoid Arthritis Among Underground Hard Rock and Other Mining Industry Workers in Colorado, New Mexico, and Utah
      JAMA Network Open
      Research
      October 17, 2022

      This cross-sectional survey study assesses whether hard rock underground mining and other mining industry occupations are associated with increased risk of rheumatoid arthritis using a population-based survey of men in counties of Colorado, New Mexico, and Utah with mining activity and high rates of silicosis-related mortality.

      Occupational Health Rheumatology Environmental Health
      Full Text | pdf link PDF open access
    • A Crowdsourcing Approach to Develop Machine Learning Models to Quantify Radiographic Joint Damage in Rheumatoid Arthritis
      JAMA Network Open
      Research
      August 29, 2022

      This diagnostic/prognostic study presents assesses machine learning algorithms submitted to an international crowdsourcing contest to develop methos to automatically quantify radiographic evidence of damage in patients with rheumatoid arthritis (RA).

      Orthopedics Rheumatology Health Informatics
      Full Text | pdf link PDF open access
    • Insurance Delays in Initiation of Tumor Necrosis Factor Inhibitors in Children With Juvenile Idiopathic Arthritis
      JAMA Network Open
      Research
      April 21, 2022

      This cohort study compares the delays in tumor necrosis factor inhibitor (TNFi) initiation because of insurance among children enrolled in public and private insurance plans.

      Rheumatology Health Care Economics, Insurance, Payment Pharmacoeconomics Health Policy Clinical Pharmacy and Pharmacology
      Full Text | pdf link PDF open access
    • Comparative Risk of Alzheimer Disease and Related Dementia Among Medicare Beneficiaries With Rheumatoid Arthritis Treated With Targeted Disease-Modifying Antirheumatic Agents
      JAMA Network Open
      Research
      April 8, 2022

      This cohort study compares incidence of Alzheimer disease and related dementia among Medicare patients with rheumatoid arthritis using disease-modifying antirheumatic drugs.

      Neurology Dementia and Cognitive Impairment Pharmacoepidemiology Rheumatology
      Full Text | pdf link PDF open access
    • What Is Rheumatoid Arthritis?
      JAMA
      Patient Information
      March 22, 2022

      This JAMA Patient Page describes the risk factors, signs and symptoms, diagnosis, treatment, and prognosis factors of rheumatoid arthritis.

      Rheumatology Patient Information JAMA Patient Information
      Full Text | pdf link PDF free
    • Development of Open-Angle Glaucoma in Adults With Seropositive Rheumatoid Arthritis in Korea
      JAMA Network Open
      Research
      March 21, 2022

      This cohort study examines whether seropositive rheumatoid arthritis is associated with an increased risk of subsequently developing primary open-angle glaucoma among adults in Korea.

      Rheumatology Glaucoma Ophthalmology
      Full Text | pdf link PDF open access
    • Association Between Immune Dysfunction and COVID-19 Breakthrough Infection After SARS-CoV-2 Vaccination in the US
      JAMA Internal Medicine
      Research
      February 1, 2022

      This cohort study compares COVID-19 incidence, risk, outcome severity, and treatment response between immunocompromised individuals and those without immune dysfunction conditions before and after SARS-CoV-2 vaccination.

      HIV Infectious Diseases Rheumatology Transplantation Coronavirus (COVID-19)
      Full Text | pdf link PDF | CME & MOC free is active quiz
    • Therapeutic Drug Monitoring for Immune-Mediated Inflammatory Diseases
      JAMA
      Opinion
      December 21, 2021
      Clinical Pharmacy and Pharmacology Inflammatory Bowel Disease Rheumatology
      Full Text | pdf link PDF
    • Effect of Therapeutic Drug Monitoring vs Standard Therapy During Maintenance Infliximab Therapy on Disease Control in Patients With Immune-Mediated Inflammatory Diseases: A Randomized Clinical Trial
      JAMA
      Research
      December 21, 2021

      This randomized clinical trial assesses the effect of therapeutic drug monitoring vs standard therapy on sustained disease control without disease worsening among patients with immune-mediated inflammatory diseases (rheumatoid arthritis, spondyloarthritis, psoriatic arthritis, ulcerative colitis, Crohn disease, or psoriasis) undergoing maintenance therapy with infliximab.

      Clinical Pharmacy and Pharmacology Gastroenterology Inflammatory Bowel Disease Psoriasis Rheumatology
      Full Text | pdf link PDF | CME & MOC free is active quiz
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