Explore the latest in rheumatology from The JAMA Network, including advances in therapy for rheumatoid and psoriatic arthritis and other connective tissue diseases.
This systematic review uses the MEDLINE and EMBASE databases to identify the available therapies for livedoid vasculopathy and their clinical outcomes.
This review summarizes characteristics, assessment, and management of Ehlers-Danlos syndromes, which can be associated with surgical complications and should be identified preoperatively to facilitate optimal treatment.
This Viewpoint examines the continued use of the name Wegner granulomatosis despite the 2011 consensus to change the name of the disease to granulomatosis with polyangiitis.
A comprehensive urine drug screen for a 50-year-old woman taking daily methadone, immediate-release morphine, gabapentin, duloxetine, and celecoxib for pain was positive for methadone and morphine but also codeine and hydromorphone. How do you interpret the results?
This cohort study examines factors associated with clinical remission of skin disease in dermatomyositis.
This national register–based study of the public health care system in Sweden assesses the risk of incident malignant neoplasms in patients with rheumatoid arthritis treated with biological disease-modifying antirheumatic drugs.
This case series examines the prevalence and characteristics of linear nonblanching skin lesions in children with Henoch-Schönlein syndrome.
This case report describes a patient with purpura annularis telangiectodes of Majocchi associated with the initiation and rechallenge of apremilast for psoriasis vulgaris
This cohort study tests the a priori hypothesis that gene expression profiles would complement clinical and histopathologic evaluations in identifying well-characterized diseases and in subdividing nonspecific orbital inflammation into clinically relevant groups.
This study uses Nationwide Inpatient Sample data to investigate the effects of abdominoplasty procedures on patients with autoimmune connective tissue diseases
A woman in her 50s with a history of systemic lupus erythematosus, congestive heart failure, and diabetes presents to the emergency department with worsening abdominal pain and a 4-day history of progressively worsening abdominal pain and diarrhea. What is your diagnosis?
A woman in her 80s presented with a 1-year history of blanchable, salmon-colored, monomorphic macules and fine telangiectasias localized to her right lower leg. What is your diagnosis?
This observational cohort study investigates the association between treatment of psychiatric disorders and skin-restricted lupus remission in a patient cohort over 2.5 years.
This case report describes a patient who developed postirradiation lichen sclerosus et atrophicus.
A 67-year-old man with granulomatous polyangiitis treated with prednisone and azathioprine has a positive galactomannan enzyme immunoassay and fungal cultures positive for Aspergillus fumigatus in bronchoalveolar lavage fluid obtained for evaluation of dyspnea and a cavitary pulmonary nodule. How would you interpret the test results?
This Teachable Moment highlights that clinical judgement is sufficient to diagnose fibromyalgia, and antinuclear antibody and subserology testing is not essential to rule out autoimmune conditions in the absence of suggestive signs and symptoms.