Explore the latest in rheumatology, including advances in therapy for rheumatoid and psoriatic arthritis and other connective tissue diseases.
This Medical Letter review summarizes doses and formulations of 2 recently approved treatments for osteoarthritic knee pain, a single-injection hyaluronic acid gel (Durolane) and an extended-release formulation of triamcinolone acetonide (Zilretta).
In this narrative medicine essay, the author shares how he assembled the tools to help him manage his pain from fibromyalgia and argues for reuniting pain medicine with compassion.
This Teachable Moment describes the case of a 58-year-old man with bilateral knee osteoarthritis who presented to the emergency department with 1 week of dizziness and intermittent dark stools.
This longitudinal cohort study of nearly 200 000 women participating for 20 years in the Nurses’ Health Study and the Nurses’ Health Study II assesses whether an association exists between depression and risk of incident systemic lupus erythematosus.
A woman in her early 30s with a history of hypertension and opioid abuse presents with painful proptosis and mild epistaxis of the right eye. Two weeks later, proptosis and periocular edema develop in the left eye. Neither condition is related to trauma. What would you do next?
This cohort study examines the association of screening for hypogammaglobulinemia with the risk of infection and mortality in patients who received rituximab therapy.
This Patient Page describes vasculitis, focusing especially on skin vasculitis, how to recognize it, and how it might be treated.
This randomized clinical trial examines the efficacy of low-dose amitriptyline vs an active comparator in reducing pain, disability, and work absence and hindrance in individuals with chronic low back pain.
This cohort study uses data from the UK Health Improvement Network to examine the association of allopurinol use in patients with gout with the risk of developing chronic kidney disease stage 3 or higher.
This cohort study evaluates outcomes of rituximab treatment in patients with different clinical subtypes of cutaneous lupus erythematosus and associated systemic disease.
This register-based case-control and cohort study estimates the risk of thyroxine-treated autoimmune thyroid disease among Swedish patients with rheumatoid arthritis at different time points before and after the diagnosis of rheumatoid arthritis.
This Medical News & Perspectives article examines the proliferation of US clinics offering unproven stem cell therapies.
This narrative review summarizes current evidence regarding the pathophysiology, diagnosis, and treatment of rheumatoid arthritis.
This randomized clinical trial examines outcomes of participation in an individually designed single-patient multi-crossover (n-of-1) trial supported by a mobile app compared with usual care among patients with chronic musculoskeletal pain.
This case-control study identifies a whole-blood gene expression signature that distinguishes children with Kawasaki disease in the first week of illness from other febrile conditions.
An adult patient with a medical history of systemic lupus erythematosus and cystic fibrosis was seen with painless, rapidly declining vision in both eyes of 1-month duration. Normal findings were seen on objective examinations. What would you do next?
This randomized clinical trial assesses the effects of a positive psychological intervention on pain and functional difficulty vs a control program in veterans with knee osteoarthritis and evaluates whether this management varies by race.
This cohort study uses data from the French myositis network to identify subgroups of idiopathic inflammatory myopathies and to develop a classification scheme using clinical and serologic information.
This study estimates mean 2017 total and out-of-pocket costs for infliximab and its biosimilar infliximab-dyyb under Medicare Part D.
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