Explore the latest in salivary gland disorders from The JAMA Network, including recent advances in diagnosis and management of parotitis and salivary gland cancer.
A young boy had an enlarging right facial mass; a computed tomographic scan showed a discrete necrotic mass in the right parotid gland, and fine-needle aspirate yielded a cellular sample with spindloid features. What is your diagnosis?
A child presented with left jaw pain and symptoms of an upper respiratory infection; the swelling resolved leaving a firm, slightly mobile, subcentimeter mass palpable in the anterior parotid gland that enlarged and became painful. What is your diagnosis?
This cohort study compares the outcomes of sialendoscopy procedures in patients who underwent general anesthesia with endotracheal intubation or monitored anesthesia care.
A man presented with an intraoral cystic lesion of the left lower lip; the lesion had developed spontaneously and grew slowly but progressively, and there was an outflow of a clear serous fluid on palpation. What is your diagnosis?
A woman presented with a 6-month history of intermittent left facial swelling and pain; she noted a discretely palpable mass in the left parotid region, which days later acutely worsened. What is your diagnosis?
A woman presented with right submandibular swelling and pain, associated with eating, and inability to express saliva on examination; a sialogram showed a high-grade stricture into the right submandibular duct orifice. What is your diagnosis?
A man presented with a 5-year progression of facial asymmetry and a 2-week history of left-sided facial weakness, pain, and otalgia; a biopsy revealed dense subcutaneous tissue overlying and invading the parotid gland. What is your diagnosis?
A man had a right parotid mass infiltrating the overlying facial skin and a postauricular node; MRI showed infiltration into the cartilaginous tissue of the external auditory canal, ipsilateral cervical adenopathy, and possible perineural involvement of the facial nerve. What is your diagnosis?
This medical record review describes facial nerve reconstruction using concurrent masseteric nerve transfer and cable grafting in patients undergoing radical parotidectomy.
This review assesses the utility of intraoperative facial nerve monitoring in 2 groups of patients undergoing partial and total parotidectomies.
A young black man had progressive bilateral parotid swelling; radiologically, there were no masses or sialoliths, and his only associated symptoms were fevers and fatigue. What is your diagnosis?
A man had a left parotid gland lesion, with no associated pain, facial numbness, or weakness; computed tomography revealed a well-circumscribed ovoid lesion in the anterior aspect of the superficial lobe of the left parotid gland. What is your diagnosis?
This study of patient records in the National Cancer Database examines the incidence of 30-day unplanned readmission for patients undergoing parotidectomy for treatment of parotid cancer.
This retrospective cohort study reviews a single institution’s experience with salivary duct carcinoma over a 20-year period, focusing on demographics, presentation, treatment, and outcome.
This population-based study describes the epidemiologic features of parotid gland involvement in sarcoidosis, with an emphasis on clinical characteristics, in a geographically well-defined population.
This medical record review examines whether the CRTC1/MAML2 fusion transcript is associated with disease stage, tumor grade, and survival in patients with mucoepidermoid carcinoma.
This retrospective cohort study reports clinical outcomes of the 4-duct ligation procedure in a consecutive series of pediatric patients with sialorrhea and characterizes patient and caregiver satisfaction.
This case report profiles a patient with advanced parotid gland cancer with BRAF kinase domain duplication whose disease responded to RAF-directed therapy; comprehensive genomic profiling identified this phenomenon across multiple tumor types.
This population-based study uses SEER data to assess 5- and 10-year survival rates among US patients with carcinoma of the minor salivary gland.
A CT scan of the neck of a woman who had slowly enlarging neck mass showed a cystic neck mass in the left floor of mouth; a core biopsy specimen showed a well-differentiated papillary neoplasm with hyalinized fibrovascular cores and degenerative changes. What is your diagnosis?