Explore the latest in sepsis, including recent consensus definitions and advances in prevention, detection, and management of the syndrome.
This cohort study assesses the incidence and outcomes of SARS-CoV-2–associated sepsis vs presumed bacterial sepsis by using objective electronic clinical criteria at 5 Massachusetts hospitals.
This cohort study estimates the population-based sepsis incidence in Sweden using administrative data and clinical medical record review.
This cohort study assesses the validity and timeliness of the Sepsis Prediction Model compared with the Systemic Inflammatory Response Syndrome (SIRS), Sequential Organ Failure Assessment (SOFA), and quick Sepsis-Related Organ Failure Assessment (qSOFA).
This Viewpoint discusses Hospital Sepsis Program Core Elements, a set of guidance provided by the Centers for Disease Control and Prevention to help hospitals develop multiprofessional programs that monitor and optimize management and outcomes of sepsis.
This mendelian randomization study evaluates whether genetically predicted insomnia is associated with risk of sepsis.
This cohort study measures the associated long-term effects of COVID-19 that are distinct from the risks associated with hospitalization for acute illnesses in general.
This essay describes the author’s experience after surviving a 40-day in-hospital treatment for septicemia from Staphylococcus endocarditis on a prosthetic aortic valve.
This randomized clinical trial compares the effect of continuous administration of meropenem vs intermittent administration on a composite outcome of mortality and emergence of pandrug-resistant or extensively drug-resistant bacteria in critically ill patients with sepsis.
This cohort study determines the disparities associated with central line–associated bloodstream infection (CLABSI) rates in pediatric patients from minoritized racial, ethnic, and language groups.
This randomized clinical trial assesses the effect of Xuebijing injection vs placebo on 28-day mortality among patients with sepsis.
This cohort study assesses the prevalence of urinary tract infections (UTIs), bacteremia, and bacterial meningitis among infants systematically tested for SARS-CoV-2 and non–SARS-CoV-2 viruses, with a focus on invasive bacterial infections.
This cohort study examines the diagnosis of bacteremia in children and youths with sickle cell disease who present to the emergency department with fever.
This review summarizes the 4 phases of fluid therapy used for critically ill patients with sepsis: resuscitation, optimization, stabilization, and evacuation.
This cohort study uses data from electronic health records to assess variability in a sepsis prediction model across 9 hospitals.
This essay describes a physician-patient’s experience with unchanged practice patterns despite the publication of new data challenging those patterns.
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