Explore the latest in sepsis, including recent consensus definitions and advances in prevention, detection, and management of the syndrome.
This randomized clinical trial examines whether lower tidal volume ventilation facilitated by extracorporeal carbon dioxide removal, compared with standard care, will decrease mortality 90 days after randomization in patients with acute hypoxemic respiratory failure.
This clinical trial compares the effectiveness of a low-normal Pao2 target vs a high-normal Pao2 target to reduce organ dysfunction in critically ill patients with systemic inflammatory response syndrome.
This cohort study examines temporal trends and variations in time-to-antibiotics for sepsis in the US Department of Veterans Affairs health care system.
This cohort study compares rates of perinatal complications among pregnant individuals with and without antepartum sepsis hospitalization.
This cohort study externally validates the Epic Sepsis Model in the prediction of sepsis and evaluates its potential clinical impact compared with usual care.
This study examines the associations of corticosteroid bursts with severe adverse events, including gastrointestinal bleeding, sepsis, pneumonia, and glaucoma, in children.
This cohort study assesses the association between the annual volume of patients with sepsis treated in intensive care units of UK hospitals and hospital mortality from sepsis between 2010 and 2016.
This cohort study evaluates whether positive fluid balance among non–critically ill patients with sepsis was associated with increased readmission risk, including readmission for heart failure.
This cohort study uses data from the Minimum Data Set and Medicare hospitalization records to assess the association between infection-related hospitalization and cognitive function among nursing home residents 65 years or older.
This prognostic study uses machine learning and electronic medical record data to develop and test an automated bacterial sepsis decision support tool for immunocompromised recipients of allogeneic hematopoietic cell transplant.
This study assesses a 2-gene RNA signature that can be translated into a rapid (<25 minutes) and portable laboratory-on-a-chip platform suitable for development as a point-of-care test.
This cross-sectional study examines disparities by race/ethnicity in interhospital transfer among among Medicare-enrolled patients with conditions previously found to have a potential mortality benefit from transfer.
This randomized trial compares the effect of vitamin C, thiamine, and hydrocortisone vs matching placebo on 30-day ventilator- and vasopressor-free days among patients with sepsis-induced respiratory and/or cardiovascular dysfunction.
This cohort study examines a virtually enabled biorepository and electronic health record (EHR)–embedded tool for use in precision medicine in patients with sepsis.
This cohort study assesses the risk of severe maternal morbidity or mortality among women with a physical, sensory, or intellectual/developmental disability compared with women without disabilities.
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: