Explore the latest in sickle cell disease, including management of pain crises, acute chest syndrome, infection prevention, and more
This case report describes fluorescein angiography results of a neonate with a combination diagnosis of incontinentia pigmenti and sickle cell trait.
This cohort study compares readmission rates in children with sickle cell disease and acute chest syndrome who receive guideline-adherent vs other antibiotic therapies.
This randomized clinical trial compares the incidence and time to onset of grade 2 or higher hand-foot syndrome in patients receiving pyridoxine vs placebo and identifies biomarkers predictive of hand-foot syndrome.
This case series assesses the visual function of 3 patients with sickle cell disease and temporal macular atrophy but with no visual symptoms.
This study of 2 population cohorts of African Americans compares hemoglobin A1c values among those with vs without sickle cell trait to determine whether the trait interferes with identification of prediabetes or diabetes.
This cross-sectional study assesses the feasibility of using administrative claims data to identify receipt of transcranial Doppler screening among children and adolescents with sickle cell anemia.
This case report describes a man in his 30s with a history of sickle cell disease and tonic-clonic seizures.
This randomized trial determines if longer-storage RBCs are inferior to shorter-storage RBCs for tissue oxygenation as measured by reduction in blood lactate levels and cerebral tissue oxygen saturation among children with severe anemia.
This case series report describes the use of optical coherence tomographic angiography to identify macular vascular abnormalities in the eyes of patients with sickle cell disease.
This Viewpoint discusses the use of racial and other descriptors in medical histories.
Naik and coauthors describe the relationship between sickle cell trait (SCT) and chronic kidney disease (CKD) and albuminuria in 2233 self-identified African Americans in the United States.
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