Explore the latest in sickle cell disease, including management of pain crises, acute chest syndrome, infection prevention, and more
This cross-sectional study examines the associations of educational attainment, employment status, and mental health with pain episode frequency and severity among individuals with sickle cell disease.
This Viewpoint discusses developing new sickle cell disease adult care models to support specialized health care homes that are patient-focused and antiracist, rather than an approach focused mainly on financial incentives.
A 61-year-old man with uncontrolled increased intraocular pressure after cataract surgery was treated with acetazolamide. Three days later, he developed acute chest pain requiring emergency treatment. What would you do next?
This cross-sectional study investigates changes in the use of hydroxyurea among youths insured by Medicaid with sickle cell anemia after the 2014 revision of clinical guidelines.
This cross-sectional study of deliveries in US hospitals examines pregnancy outcomes for people with sickle cell disease (SCD) and compares adverse outcomes with Black and Non-Black populations without SCD.
This cross-sectional study compares rates and odds of severe maternal morbidity and other adverse pregnancy outcomes among Black pregnant individuals with sickle cell disease vs anemia.
This cohort study of children with sickle cell disease (SCD) in a French hospital system examines the association of 13-valent pneumococcal conjugate vaccine implementation with incidence of acute chest syndrome (ACS).
This genetic association study assesses the association of sickle cell trait with prepandemic health conditions in Million Veteran Program participants and assesses the severity and sequelae of COVID-19.
This Review summarizes the pathophysiology and diagnosis for sickle cell disease (SCD), management for SCD and its related complications, and prognosis for patients with SCD.
This cohort study investigates the association between sickle cell trait and risk of stillbirth in pregnant people.
This review discusses how systematic data collection for sickle cell disease through a longitudinal clinical registry and a national surveillance program can improve resource use and patient outcomes and provide an equitable foundation for care.
This cohort study examines whether hydroxyurea use changes in young adults with sickle cell disease who are transitioning from pediatric to adult health care.
This study examines the association between prescription drug monitoring program mandates and changes in opioids dispensed to patients with sickle cell disease or cancer with bone metastasis who presented to the emergency department in 29 US states.
This economic evaluation estimates the budget impact and affordability of a gene therapy for severe sickle cell disease from the perspective of US Medicaid programs with the highest prevalence of sickle cell disease while exploring the impact of an annuity payment model.
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