Explore the latest in gastric cancer, including advances in understanding the epidemiology, diagnosis, management, and prevention of the disease.
This nonrandomized controlled trial investigates whether the addition of pembrolizumab to perioperative chemotherapy in patients with locally advanced, resectable gastric and gastroesophageal junction adenocarcinoma increases pathologic complete response and whether the addition of maintenance pembrolizumab improves disease-free survival.
This cohort study analyzes the trends in incidence, tumor characteristics, staging, and treatment of noncardia gastric cancer among patients in the Netherlands from 1989 to 2021.
This randomized clinical trial investigates the 5-year survival outcomes of laparoscopy-assisted distal gastrectomy compared with open distal gastrectomy for the management of advanced gastric cancer.
This cohort study examines the association of esophagogastric cancer with bariatric surgery in a large national cohort.
This randomized clinical trial assesses whether laparoscopic proximal gastrectomy with double-tract reconstruction is superior to laparoscopic total gastrectomy for the surgical treatment of patients with early gastric cancer in the upper third of the stomach.
This cost-effectiveness analysis of a randomized clinical trial investigates the cost-effectiveness of laparoscopic compared with open gastrectomy for gastric cancer.
This randomized clinical trial compares the long-term and short-term efficacy of laparoscopic total gastrectomy and conventional laparoscopic total gastrectomy for patients with advanced proximal gastric cancer that has not invaded the greater curvature.
This cohort study uses whole-exome and targeted sequencing to assess the incidence rate of CDH1 germline alterations in hereditary diffuse gastric cancer, provide a genetic landscape for the disease, and identify new susceptibility genes among Chinese patients with hereditary diffuse gastric cancer.
This validation study evaluates whether diffuse reflectance spectroscopy on gastric and esophageal cancer specimens can differentiate tissue types and provide real-time feedback to the operator.
This diagnostic study develops and validates a deep learning algorithm to predict Epstein-Barr virus status from pathology images of gastric cancer.
This randomized clinical trial investigates the oncologic safety profile of laparoscopic distal gastrectomy compared with open gastrectomy for the treatment of clinically advanced gastric cancer.
This systematic review and meta-analysis examines the predictive value of tissue-based PD-L1 status compared with other variables for ICI benefit among 17 randomized clinical trials including 11 166 patients with advanced gastroesophageal cancer.
This cohort study characterizes the clinical and genomic features of patients with brain metastasis from gastroesophageal adenocarcinoma and evaluates the associations of surgical resection and radiotherapy use with survival.
This case-control study involving a secondary analysis of a randomized clinical trial assesses whether new gastric cancer can be detected approximately 1 year after early gastric cancer detected by intensive index endoscopic examination among patients with a high risk of gastric cancer.
This cross-sectional study examines trends in cancer mortality among Black individuals in the US from 1999 to 2019 and compares mortality rates in 2019 between the Black population and other racial and ethnic populations.
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