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    Addiction Medicine

    Explore the latest in substance use and addictive disorders, including topics in smoking cessation and treatment of opioid and alcohol use disorders.

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    • Survey of Barriers and Facilitators to Prescribing Buprenorphine and Clinician Perceptions on the Drug Addiction Treatment Act of 2000 Waiver
      JAMA Network Open
      Research
      May 12, 2022

      This survey study examines barriers to and facilitators of obtaining a waiver to prescribe buprenorphine among office-based clinicians in Texas.

      Opioids Health Policy
      Full Text | pdf link PDF open access
    • Changes in US Clinician Waivers to Prescribe Buprenorphine Management for Opioid Use Disorder During the COVID-19 Pandemic and After Relaxation of Training Requirements
      JAMA Network Open
      Research
      May 12, 2022

      This case series examines numbers of US clinicians receiving waivers from the Drug Enforcement Administration allowing them to prescribe buprenorphine for opioid use disorder before and during the COVID-19 pandemic.

      Opioids Health Policy Coronavirus (COVID-19)
      Full Text | pdf link PDF open access
    • Beyond the Waiver: Multilevel Interventions Needed to Expand Buprenorphine Treatment
      JAMA Network Open
      Opinion
      May 12, 2022
      Opioids Health Policy Coronavirus (COVID-19)
      Full Text | pdf link PDF open access
    • Analysis of Stimulant Prescriptions and Drug-Related Poisoning Risk Among Persons Receiving Buprenorphine Treatment for Opioid Use Disorder
      JAMA Network Open
      Research
      May 11, 2022

      This cohort study with a case-crossover analytical design examines the associations between prescription stimulant use and drug-related poisonings and buprenorphine treatment retention among patients with opioid use disorder.

      Attention Deficit/Hyperactivity Disorders Clinical Pharmacy and Pharmacology Psychiatry and Behavioral Health Opioids Adverse Drug Events
      Full Text | pdf link PDF open access
    • Stimulant Prescription Medications Among Persons Receiving Buprenorphine for Opioid Use Disorder With Prior Drug-Related Poisoning—Evidence of Net-Sum Gain
      JAMA Network Open
      Opinion
      May 11, 2022
      Attention Deficit/Hyperactivity Disorders Clinical Pharmacy and Pharmacology Psychiatry and Behavioral Health Opioids Adverse Drug Events
      Full Text | pdf link PDF open access
    • Suicide Attempt and Risk of Substance Use Disorders Among Female Youths
      JAMA Psychiatry
      Research
      May 11, 2022

      This cohort study assesses whether suicide attempts by females aged 8 to 19 years in Quebec, Canada, are associated with subsequent risk of substance use disorders later in life.

      Psychiatry and Behavioral Health Child and Adolescent Psychiatry Adolescent Medicine Suicide
      Full Text | pdf link PDF
    • Comparative Effectiveness Associated With Buprenorphine and Naltrexone in Opioid Use Disorder and Cooccurring Polysubstance Use
      JAMA Network Open
      Research
      May 10, 2022

      This comparative effectiveness study evaluates distribution of buprenorphine and naltrexone initiation among individuals with opioid use disorder with or without cooccurring substance use disorder.

      Opioids Pharmacoeconomics
      Full Text | pdf link PDF open access
    • Mental Health and Substance Use Among Homeless Adolescents in the US
      JAMA
      Research
      May 10, 2022

      This study uses data from the state-level Youth Risk Behavioral Survey to evaluate mental health and substance use outcomes among homeless and nonhomeless adolescents in 2019.

      Psychiatry and Behavioral Health Child and Adolescent Psychiatry Adolescent Medicine Pediatrics
      Full Text | pdf link PDF
    • Effect of Mailing an At-home Disposal Kit on Unused Opioid Disposal After Surgery: A Randomized Clinical Trial
      JAMA Network Open
      Research
      May 6, 2022

      This randomized clinical trial tests the effect of a mailed, at-home disposal kit on disposal rates of unused opioids after surgery.

      Orthopedics Surgery Opioids Pain Medicine
      Full Text | pdf link PDF open access
    • Efficacy and Safety of Difelikefalin in Japanese Patients With Moderate to Severe Pruritus Receiving Hemodialysis: A Randomized Clinical Trial
      JAMA Network Open
      Research
      May 5, 2022

      This randomized clinical trial evaluates the efficacy, dose response, safety, and pharmacokinetics of 3 different doses of difelikefalin compared with placebo for the treatment of moderate to severe pruritus among Japanese patients receiving hemodialysis.

      Nephrology Opioids Renal Replacement
      Full Text | pdf link PDF open access
    • Evaluation of Trends in Alcohol Use Disorder–Related Mortality in the US Before and During the COVID-19 Pandemic
      JAMA Network Open
      Research
      May 4, 2022

      This cross-sectional study uses US vital statistics data to evaluate alcohol use disorder–related mortality rates from 2012 to 2021, with a focus on trends during the COVID-19 pandemic.

      Public Health Alcohol Coronavirus (COVID-19)
      Full Text | pdf link PDF | CME & MOC open access is active quiz
    • Mindfulness-Based Therapy Reduces Chronic Pain and Opioid Misuse
      JAMA
      News
      May 3, 2022
      Pain Medicine Complementary and Alternative Medicine Opioids Psychiatry and Behavioral Health Physical Medicine and Rehabilitation
      Full Text | pdf link PDF
    • Alcohol-Related Deaths During the COVID-19 Pandemic
      JAMA
      Research
      May 3, 2022

      This study uses mortality data from the National Center for Health Statistics to assess whether alcohol-related deaths increased during the COVID-19 pandemic.

      Public Health Population Health Coronavirus (COVID-19) Alcohol
      Full Text | pdf link PDF | CME & MOC free is active quiz
    • Implementation of a Standardized Clinical Definition of Opioid Withdrawal in the Neonate: Challenges and Opportunities
      JAMA
      Opinion
      May 3, 2022

      This Viewpoint discusses increases in opioid use disorder among pregnant people during the US opioid crisis and recommendations to define, diagnose, and treat neonatal abstinence syndrome and neonatal opioid withdrawal syndrome.

      Pregnancy Opioids Antenatal Exposures and Child Outcomes Obstetrics Women's Health
      Full Text | pdf link PDF
    • Opioid and Naloxone Prescribing Following Insertion of Prompts in the Electronic Health Record to Encourage Compliance With California State Opioid Law
      JAMA Network Open
      Research
      May 2, 2022

      This cohort study examines changes in naloxone and opioid prescribing rates in the outpatient setting at 1 integrated health care system after the launch of decision-support prompts in the electronic health record (HER) in compliance with the State of California Assembly Bill 2760.

      Health Policy Health Informatics Electronic Health Records Opioids Pain Medicine
      Full Text | pdf link PDF open access
    • Potential Value of Concurrent Implementation of Regulatory Measures and Electronic Interventions
      JAMA Network Open
      Opinion
      May 2, 2022
      Health Policy Health Informatics Electronic Health Records Opioids Pain Medicine
      Full Text | pdf link PDF open access
    • Curing Hepatitis C—Requires More Than a Prescription
      JAMA Internal Medicine
      Opinion
      May 1, 2022
      Infectious Diseases Viral Hepatitis Hepatitis C Hepatobiliary Disease Health Care Delivery Models
      Full Text | pdf link PDF
    • Racial Disparities in Opioid Overdose Deaths in Massachusetts
      JAMA Network Open
      Research
      April 28, 2022

      This cross-sectional study evaluates publicly available data from Massachusetts on reporting trends in opioid-related overdose deaths by race and ethnicity.

      Opioids Health Inequities Toxicology Diversity, Equity, and Inclusion Health Disparities
      Full Text | pdf link PDF open access
    • Association of Opioid Dose Reduction With Opioid Overdose and Opioid Use Disorder Among Patients Receiving High-Dose, Long-term Opioid Therapy in North Carolina
      JAMA Network Open
      Research
      April 27, 2022

      This cohort study assesses the association of rapid reduction or discontinuation of opioid therapy with overdose and opioid use disorder (OUD) among patients receiving high-dose, long-term opioid therapy in North Carolina.

      Public Health Pharmacy and Clinical Pharmacology Clinical Pharmacy and Pharmacology Opioids Toxicology
      Full Text | pdf link PDF open access
    • Trends in Prevalence of Cigarette Smoking Among US Adults With Major Depression or Substance Use Disorders, 2006-2019
      JAMA
      Research
      April 26, 2022

      This exploratory study was conducted to examine trends in cigarette smoking among adults with and without a major depressive episode, substance use disorder, or both and by age, sex, and race and ethnicity.

      Psychiatry and Behavioral Health Tobacco and e-Cigarettes Lifestyle Behaviors
      Full Text | pdf link PDF
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