Explore the latest in substance use and addictive disorders from The JAMA Network, including topics in smoking cessation and treatment of opioid and alcohol use disorders.
This randomized clinical trial compares the effectiveness of extended-release naltrexone with that of buprenorphine-naloxone in maintaining short-term abstinence from heroin and other illicit substances.
This systematic review and meta-analysis outlines the evidence for nonpharmacological interventions for postoperative pain management after total knee arthroplasty.
This population-based, case-control, family aggregation study examines the frequency and range of neuropsychiatric conditions that occur within individual first-degree and second-degree relatives of patients with amyotrophic lateral sclerosis.
In this Viewpoint, former CDC Director Tom Frieden outlines 10 steps the federal government should take to prevent opioid addiction among nonusers and treat addiction and prevent overdoses among current users.
In this Viewpoint, authors from the US CDC’s National Center for Injury Prevention and Control discuss infrastructure investments, legal changes, and clinical and public health strategies for reducing overdose deaths among opioid users.
This Viewpoint argues that pediatric physicians must revisit their approach to screening adolescents and young adults for marijuana use and initiating conversations about its associated health consequences with patients and their parents.
This observational cohort study determines the opioid prescribing patterns among ophthalmologists and elucidates ophthalmologists’ role in the prescription opioid abuse epidemic.
This multisite, double-blind, within-participant assessment examines the dose-dependent association of cigarettes with reduced nicotine content with the reinforcing effects, subjective effects, and smoking topography in populations with psychiatric and socioeconomic vulnerabilities.
This systematic review and meta-analysis estimates prevalence of fetal alcohol spectrum disorder among children and youth in the general population by country and international region.
This multicenter cohort study examines the procedural sedation practices, adverse events, and risk factors for children undergoing painful procedures in Canadian emergency departments.
This study uses data from the Premier Alliance database to assess factors associated with the use of smoking cessation pharmacotherapy in smokers hospitalized for coronary heart disease.
This randomized clinical trial examines whether collaborative care for patients with opioid and/or alcohol use disorders improves the delivery of evidence-based treatments and increases self-reported abstinence compared with usual primary care.
This Viewpoint describes an organization created to share stories and experiences of medical professionals.
This population-based study examines the incidence of opioid prescription at discharge in adult military health care beneficiaries hospitalized for trauma.
This cohort study uses data from the Department of Defense Military Health System Data Repository to describe patterns of opioid pain medication prescriptions after common surgical procedures and determine the appropriateness of the prescription as indicated by the rate of refills.