Explore the latest in diabetes from The JAMA Network, including advances in screening, prevention, diagnosis, and treatment of the disease.
A woman in her 50s with a history of systemic lupus erythematosus, congestive heart failure, and diabetes presents to the emergency department with worsening abdominal pain and a 4-day history of progressively worsening abdominal pain and diarrhea. What is your diagnosis?
This Clinical Evidence Synopsis summarizes a Cochrane review on the effects of adding oral hypoglycemic agents to insulin for patients with type 2 diabetes mellitus who have not achieved optimal glycemic control with insulin alone.
This phase 2 randomized trial compared the effects on hemoglobin A1c levels of varying doses of oral once-daily semaglutide vs placebo vs subcutaneous semaglutide in patients with type 2 diabetes.
This cohort simulation model evaluates the use of tests and treatment of latent tuberculosis infection in residents born outside the United States.
This cohort study of US women participating in the Nurses’ Health Study II prospectively evaluates the association of a history of gestational diabetes with incident cardiovascular risk.
This cohort study uses Medicaid claims data to assess the association between antidepressant use and the risk of incident type 2 diabetes among youths by antidepressant subclass and duration of use, cumulative dose, and average daily dose.
This population-based cohort study compares rates of severe hypoglycemia and diabetic ketoacidosis among children, adolescents, and young adults with type 1 diabetes managed with insulin pump therapy vs insulin injection therapy.
This JAMA Clinical Guidelines Synopsis summarizes the 2016 practice guideline on management of diabetic foot sponsored by the Society for Vascular Surgery in collaboration with the American Podiatric Medical Association and the Society for Vascular Medicine.
This cohort study tests the association between early-life antibiotic use and islet or celiac disease autoimmunity in genetically at-risk children prospectively followed up for type 1 diabetes or celiac disease.
This study develops and validates a risk stratification tool to categorize risk of future hypoglycemia-related emergency department or hospital use in patients with type 2 diabetes.
This systematic review and meta-analysis compares the incidence and risk of endocrine adverse events following treatment with US Food and Drug Administration-approved immune checkpoint inhibitor regimens.
This secondary analysis of the Insulin Resistance Intervention After Stroke trial estimates the relative and absolute effectiveness of pioglitazone after ischemic stroke or transient ischemic attack in subgroups of patients defined by pretreatment risk for stroke or myocardial infarction.
This Viewpoint discusses the potential risks of the US Food and Drug Administration’s 2016 approval of the Dexcom G5 Mobile continuous glucose monitor for making diabetes treatment decisions without confirmation of the device’s readings with fingerstick or laboratory testing.
This cross-sectional study assesses the functional burden of diabetic retinopathy across severity levels in the United States.
This Teachable Moment describes a case of a man with type I diabetes admitted to the emergency department after his insulin pump was not reattached.
This population-based study examines the use of and adherence to drugs from classes commonly used for therapy in patients with cardiovascular disease and diabetes.
This Viewpoint discusses the outcomes of the Empagliflozin Removal of Excess of Glucose Outcome trial and the optential benefits of sodium-dependent glucose cotransporter 2 in treating heart failure.