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January 1920

HISTOPATHOLOGY OF THE BRAIN AND SPINAL CORD IN A CASE PRESENTING A POSTINFLUENZAL LETHARGIC ENCEPHALITIS SYNDROME

Author Affiliations

Assistant Professor of Pathology and Bacteriology, State University of Iowa IOWA CITY

Arch NeurPsych. 1920;3(1):1-16. doi:10.1001/archneurpsyc.1920.02180130004001
Abstract

The occurrence of small epidemic foci of epidemic encephalitis in Iowa during the spring of 1919 raises the question of a new disease entity that can reach its ultimate solution only by the publication of necropsy studies and careful pathologic examinations, bearing in mind always the toxic or infectious origin of the changes. Clinically it is not always possible to differentiate toxic ophthalmoplegia with lethargy from Heine-Medin's disease, or botulism with ophthalmic symptoms.

REPORT CF CASE 

History.—  Through the courtesy of Dr. C. P. Howard, professor of internal medicine, it is possible to present the case of F. T. (Clinical No. 6075), a man, aged 37, who in January, 1919, had an attack of influenza followed by pneumonia from which he apparently completely recovered. On March 25, he was admitted to the university hospital complaining of pain and weakness in the arms and legs. Following his admission he became progressively

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