It is only recently that clinical histories have been published concerning patients suffering from heredosyphilis who have developed a syndrome identical to spinal spastic paralysis. Such cases are comparatively rare. Nonne,1 in the last edition of his book, was able to report only about ten cases, including his own private ones. I have therefore thought it opportune to report the clinical histories of three such cases, occurring in two brothers and a sister, the offspring of a syphilitic father.
REPORT OF CASES
G. V., aged 54, a tradesman, at the age of 22 suffered from what was diagnosed as soft chancres of the penis. Married soon after, his first-born, a son, remained in good health. At intervals of two years a second son, a daughter and a third son were born. The fifth child, 14 years old, seemed slightly deficient, but was free from the syndrome of
G. MINGAZZINI. FAMILY SPASTIC PARALYSIS OF SPINAL TYPE ON A HEREDOSYPHILITIC BASIS. Arch NeurPsych. 1921;5(6):637–644. doi:10.1001/archneurpsyc.1921.02180300002001