The pressing need of more effective therapy in neurosyphilis has stimulated syphilographers and neurologists to elaborate methods expressly adapted to combat the disease. These methods may be roughly divided into: (1) intensive antisyphilitic medication, including arsphenamin given intravenously, mercury and the iodids; (2) drainage of the spinal fluid, following a previous intravenous injection of arsphenamin; (3) the intraspinal methods of Swift and Ellis, Ogilvie and Byrnes. Each of these methods has produced good clinical results in the hands of competent observers, but each has certain inherent defects. Sachs1 and his co-workers feel strongly that intravenous treatments will clear up such cases as are amenable to medication. Dercum2 has obtained favorable results from complete drainage of the spinal fluid. Swift,3 Ogilvie, Byrnes and Fordyce report good results following intraspinal procedures. Other than an inclination to advise intraspinal medication in difficult cases, there has been little tendency in the