The observations of Marro and others1 have indicated the frequent occurrence of developmental defects of the reproductive apparatus and the physical characteristics of sex in idiots, cretins, epileptic persons, criminals, and persons with mental disease beginning at puberty. In male patients, varicocele, undescended testicle, hernia, hypospadias, unusually large and small testicles, deficiency of pubic hair and beard, and disturbance in skeletal growth, were reported to be more frequent than in controls. These observations were made before there was much evidence to indicate that certain endocrine glands are in some way essential to the normal development and functional activity of the reproductive apparatus.More recently Emerson has reported the frequency of a type of imperfect physical development called "status lymphaticus" in alcoholic patients2 and in patients with dementia praecox.3 He found this type in 22 per cent. of 1,000 alcoholic and drug cases in the alcoholic
GIBBS CE. SEX DEVELOPMENT AND BEHAVIOR IN MALE PATIENTS WITH DEMENTIA PRAECOX. Arch NeurPsych. 1923;9(1):73–87. doi:10.1001/archneurpsyc.1923.02190190078007
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