Decerebrate animals have been produced chiefly by ablation of the cerebrum and interbrain or transection of the brain stem.
These mutilating operations are attended by a high mortality and associated with a great degree of shock. The exact level of decerebration cannot be predetermined and complete decerebration is not assured until postmortem examination. Frequently some part of the brain cephalad to the decerebration remains intact. Hemorrhage is uncontrolled and the degree of hemorrhage immeasurable. The shock obscures the picture and the time of its disappearance cannot be accurately determined. An animal decerebrated by such methods shows symptoms which result not only because of the operative removal of function of certain parts of the brain, but also because of compression by hemorrhage, shock and mutilation of an immeasurable area of tissue adjacent to the operative wound.
Other methods have been employed to destroy certain parts of the nervous system; for example
POLLOCK LJ, DAVIS LE. STUDIES IN DECEREBRATION: I. A METHOD OF DECEREBRATION. Arch NeurPsych. 1923;10(4):391–398. doi:10.1001/archneurpsyc.1923.02190280012002
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