Cushing and Ayer recently1 called attention to the unusual finding of xanthrochromia and increased protein in the spinal fluid above tumors of the cauda equina. This syndrome is most confusing in the localization of cauda equina tumors. That a "Froin syndrome" signifies spinal cord compression, due to tumor or other lesion, sufficiently marked to form a closed cavity and stasis of the fluid in the lumbar culdesac below the lesion, has been generally accepted. Cushing and Ayer report five cases of caudal tumor in which this syndrome was observed—a unique report. The following case report is submitted as another illuminating example:
REPORT OF CASE
—A. B., aged 60, a public accountant, was seen Jan. 12, 1923, because of severe neuralgic attacks along the course of the right anterior crural nerve. The family and personal histories were negative. About August, 1921, he had noticed discomfort and soreness in
Hammes EM. A TUMOR OF THE CAUDA EQUINA WITH THE FROIN SYNDROME. Arch NeurPsych. 1924;11(1):82–84. doi:10.1001/archneurpsyc.1924.02190310088007
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