The occurrence of pronounced disturbance of respiratory rhythm, often associated with changes in posture and character, following epidemic encephalitis, especially in children, has been reported. The condition is generally regarded as a sequel to the encephalitic attack, as pointed out by Parker in a paper1 in which he reviewed the literature and reported the findings in eight cases. Owing to certain extremely specific effects which I have observed following the injection of a streptococcus with peculiar neurotropic properties, which has been isolated consistently from cases of encephalitis and epidemic hiccup, I thought that possibly a similar organism might bear etiologic relationship to these strange manifestations. Through the cooperation of Dr. Helmholz and Dr. Shelden, of the Mayo Clinic, I have had opportunity to test this hypothesis.
The technic employed was similar to that used in my studies in encephalitis and epidemic hiccup.2 Suffice to say that intracerebral or
EDWARD C. ROSENOW. EXPERIMENTS ON THE ETIOLOGY OF RESPIRATORY ARRHYTHMIAS FOLLOWING EPIDEMIC ENCEPHALITIS. Arch NeurPsych. 1924;11(2):155–178. doi:10.1001/archneurpsyc.1924.02190320049006