In the diagnosis and treatment of intracranial infections and neoplastic diseases, one desires more detailed anatomic knowledge of the cerebrospinal fluid system. Indeed, since the great contribution of Key and Retzius in 1875, little has been added to this knowledge, and the present work has been undertaken in a desire to correct this dearth of detailed information.
Galen,1 father of anatomy, and Vesalius,2 in the sixteenth century, described a thin membrane surrounding the brain underneath the dura, but neither of them recognized the arachnoid membrane or the subarachnoid space. In fact, the arachnoid was not established as a membrane separate from the pia mater until the middle of the seventeenth century. It was given its name by Blaes (Blasius),3 an anatomist of Amsterdam (1626-1682), arachnoid being derived from the Greek word ∥páϰm, meaning a spider's web. Soon afterward, Varioli, an Italian investigator, showed that this membrane
LOCKE CE, NAFFZIGER HC. THE CEREBRAL SUBARACHNOID SYSTEM. Arch NeurPsych. 1924;12(4):411–418. doi:10.1001/archneurpsyc.1924.02200040054004
Customize your JAMA Network experience by selecting one or more topics from the list below.