In considering the individual personality, whether in health or disease, one must recognize the fundamental proposition that persons differ in their reactions to the various forces and experiences they encounter in the environment. These differences are in large part determined by factors inherent in the individual constitution.
One may gain a well formulated conception of what is implied in the connotation of constitution as it pertains to the problems of pathology from the statement of Bauer1 in his work on "Constitutional Disposition to Disease." In discussing the variability of individual disposition to disease, he states: "This variability rests on the individual and temporal differences of the body states. This, in turn, results from two factors: first, those qualities that are transmitted in the germ plasm or those qualities that are laid down at the moment of fertilization, and, second, the multiform intra- and extra-uterine acquisitions, influences and adaptations of
BARRETT AM. HEREDITARY AND FAMILIAL FACTORS IN THE DEVELOPMENT OF THE PSYCHOSES. Arch NeurPsych. 1925;13(1):1–25. doi:10.1001/archneurpsyc.1925.02200070004001
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