Lesions of the central nervous system afford excellent opportunities for study of numerous problems pertaining to the cerebrospinal fluid. While some facts obtained from histopathologic studies correspond to, others seem to be at variance with experimental findings.
According to prevalent views, the cerebrospinal fluid originates in the lateral ventricles from the choroid plexus. Some (Studnicka,1 Kafka2) maintain that the ependymal cells of the ventricles and the spinal canal as well as other formations (the "infundibular" gland, the paraphysis, the "epiphyseal" rudiments according to Studnicka) also participate in its production. Some (Weed,3 Weigeldt4) again hold that the perivascular channels of Virchow-Robin are contributory agents in the elaboration of this body fluid, while a smaller group of workers (Schmorl,5 Lewandowsky,6 Askanazy,7 Spina,8 Tilman,9 Bungardt,10 Becht,11 Klestadt12) asserts that the choroid plexus has nothing to do with the cerebrospinal fluid, the
HASSIN GB. EFFECT OF ORGANIC BRAIN AND SPINAL CORD CHANGES ON SUBARACHNOID SPACE, CHOROID PLEXUS AND CEREBROSPINAL FLUID. Arch NeurPsych. 1925;14(4):468–488. doi:10.1001/archneurpsyc.1925.02200160035005
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