Disturbances of respiration during the acute stage of epidemic encephalitis are common and include respiratory paralysis, tachypnea, bradypnea and various types of irregularity of rate or amplitude. They may be due to inflammatory changes in the respiratory organs, to bulbar lesions or to myoclonic contractions of respiratory muscles. Less commonly among the sequelae, or in what we now regard as the chronic stage of the disease, similar disturbances occur. These phenomena were classified by Marie1 into (1) disturbances of respiration proper, as tachypnea (either permanent or paroxysmal with periods of apnea), and bradypnea; (2) spasmodic cough, and (3) respiratory tics. They may be associated with other disturbances, such as the pseudo-Parkinson syndrome, or may be the predominating symptom. The most striking of these disturbances are attacks of alternate polypnea and apnea, which seem to be characteristic of this disease. Such cases have been reported by Vincent and Bernard,2
Smith WA. RESPIRATORY DISTURBANCES FOLLOWING EPIDEMIC ENCEPHALITIS. Arch NeurPsych. 1926;15(5):617–622. doi:10.1001/archneurpsyc.1926.02200230082008
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