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June 1926

A CASE OF HYDROPHOBIA WITH NEGRI BODIES IN THE BRAIN

Author Affiliations

Instructor in Neurology, Medical School of Harvard University BOSTON

Arch NeurPsych. 1926;15(6):735-737. doi:10.1001/archneurpsyc.1926.02200240063005
Abstract

Hydrophobia is such an uncommon disease that very few papers have appeared in recent years on the clinical aspect of this disease or on the pathologic findings in the human brain. Most of the work on the subject has been done on animals. The view is now generally held that the presence of Negri bodies in the brain of an animal is pathognomonic of rabies. They have rarely been found, however, at least as far as the literature on the subject is concerned, in the human brain. It is still uncertain whether the bodies described by Negri in 1903 are the true etiologic agents in the production of the disease. Their reported cultivation by Noguchi in 1913 has not been confirmed, so far as I can learn, by other workers, nor has Noguchi continued his experimental studies on these interesting bodies.

Although the following case came to my attention only

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