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August 1926

THE TREATMENT OF GENERAL PARALYSIS BY INOCULATION WITH MALARIA: A SECOND REPORT

Arch NeurPsych. 1926;16(2):182-204. doi:10.1001/archneurpsyc.1926.02200260054004
Abstract

The purpose of this second communication on the treatment of general paralysis by inoculation with tertian malaria is less a purely statistical review of the additional cases treated since the date of our first report1 than it is a more detailed discussion than was then possible of certain features of the treatment as these have been exemplified in the case records of some of our patients. Certain of these observations are of the greater significance in view of the fact that some of the patients to be discussed have now been under observation for more than two years since the treatment was completed.

Concerning the malarial infection itself we have little to add. In the great majority of cases we have noted the occurrence of the "initial fever" referred to by Korteweg2 and by Pieper and Russell,3 which the latter have described as "a continuous fever, sometimes

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