Multiple primary malignant tumors have great interest for both clinicians and pathologists. In an excellent summary of this subject Major1 calls attention to the fact that the literature contains many such reports. He adds a case of carcinoma of the face and a round cell sarcoma of the stomach. Seecof2 reports a case of carcinoma of the lung and carcinoma of the rectum, each producing metastases. It is not at all uncommon to find metastases in the brain, but primary multiple cerebral neoplasms are rare, though a few cases have been previously reported. Thus, Behrendsen3 reports a case of a cholesteatoma of the pia mater in the region of the pons, and a glioma of the left hemisphere; Bartels4 reports two cases, one of mulitple primary sarcoma of the meninges with invasion of the brain, and another of multiple endothelioma and multiple neurofibroma of the base;
Sands IJ. MULTIPLE PRIMARY CEREBRAL NEOPLASMS REPORT OF A CASE. Arch NeurPsych. 1926;16(4):447–450. doi:10.1001/archneurpsyc.1926.02200280055006
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