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Crile's early work on histologic changes, particularly in the nervous system in response to shock, trauma, anesthesia, etc., are more or less familiar to us all, as well as the fact that he has gone on from these studies to work in conductivity, temperature and physical chemistry. Furthermore, even though his hypotheses have not been universally accepted, still, like those of Cajal, they have furnished many with food for thought and a growing respect for the philosophic comprehension of the author.
In this new book, Crile's theory of life blossoms forth. He gathers together the results of his researches and those of others for the past twenty years, and announces his conception of a "Bipolar Theory of Living Processes." It is a work that cannot but hold the attention and gain the respect of the reader for the sweeping character of the views expressed. The foundations on which the theory
A Bipolar Theory of Living Processes.. Arch NeurPsych. 1926;16(6):814–816. doi:10.1001/archneurpsyc.1926.02200300134012