This is an excellent treatise on the problems of general paralysis. It is, of course, possible to offer criticisms; for instance, insufficient attention is given to American work, although the author does rarely refer to some American worker. One might criticize the handling of the subject, as too much weight at times is given to minor details and matters of considerable importance are treated lightly. The main defect, which is undoubtedly incidental to the small amount of attention given to American work, is the absence of any mention of tryparsamide. All these criticisms and others that might be made can be easily avoided in future editions, which this treatise merits. It is written by a man with long experience in the treatment of general paralysis by many methods, so he is able to discuss the subject from the standpoint of one who has worked as well as one who has