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May 1927


Arch NeurPsych. 1927;17(5):714-717. doi:10.1001/archneurpsyc.1927.02200350145011

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This work is an ambitious monograph, no. 47, of a series edited by Foerster and Wilmans. The first part has to do with experimental myoclonic epilepsy. An excellent historical review is given of such experimental methods as anemia, stimulation of the cortex, injury of the cord, and poisons. The author sets out to discover: (1) whether there is any experimental method that can give phenomena really analogous to epilepsy; (2) given such a method, what form and latency the graphically recorded convulsive movement may have, and (3) in what way lesions of the central nervous system may change the effects of a general convulsant drug. From the literature he concludes that no drug satisfies the criteria; therefore, it cannot be said that any drug produces epilepsy. Absinthe and camphor come nearest to fulfilling the desiderata, especially the latter, which causes animals to have repeated attacks closely resembling the myoclonic form

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