What, if any, specific treatment shall be given to the far advanced and practically hopeless cases of general paralysis that come under his care is one of the perplexing problems confronting the physician in a large hospital for the insane. Experience has shown that the various arsenicals, whether administered intravenously or intraspinally, are of little if any curative value in the late stages of neurosyphilis of the paralytic type.1 Tryparsamide, sulpharsphenamine and other drugs, which seem to have been of some value in combating neurosyphilis of the general paralytic type, are recommended by those most experienced in their use as promising good results only in the earlier cases. In large institutions for the insane in which there are likely to be hundreds of cases of late neurosyphilis and in which the funds are always limited, it is a serious question whether the expenditure of time and money necessary for
Petry HK. THE INTRAVENOUS USE OF MERCURIC CYANIDE IN TERMINAL GENERAL PARALYSIS. Arch NeurPsych. 1927;17(6):804–806. doi:10.1001/archneurpsyc.1927.02200360084005
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