Sudden death due to symptomless adenoma of the hypophysis is probably rare. I have been able to find only one published report in which, by title, sudden death was correlated with the presence of a previously unsuspected tumor of this organ, although cases are on record in which death occurred more or less suddenly in patients known to have such tumors.
—The patient, a man, aged 37, was brought to the Illinois Central Hospital, on the service of Dr. L. H. Sloan, in a comatose condition at noon, May 17, 1926. He was a boilermaker, and had gone to work that morning apparently feeling in normal health. About 10 o'clock, he suddenly became dizzy and began to vomit. He walked to the office of the company physician, and a few minutes after his arrival went into coma. The physician, suspecting poisoning in view of the vomiting, washed the
Esmond R. Long. ADENOMA OF THE HYPOPHYSIS WITHOUT ACROMEGALY, HYPOPITUITARISM OR VISUAL DISTURBANCES, TERMINATING IN SUDDEN DEATH. Arch NeurPsych. 1927;18(4):576–584. doi:10.1001/archneurpsyc.1927.02210040083005